What resolves this contention: On the cell-class specificity of feedforward vs…

What resolves this contention: On the cell-class specificity of feedforward vs feedback cortico-cortical connectivity in mouse visual cortex: the rabies-based input-mapping study reports broadly similar long-distance input patterns for FF and FB neurons, whereas the channelrhodopsin-mapping study reports strong looped-cell-class selectivity of FF/FB inputs in deep layers; the conflict reflects different read-outs (presynaptic input counts vs postsynaptic EPSC strength) and different layers analyzed. / Overall, long-distance input patterns for these feedforward and feedback neurons were largely similar, as all received the majority of their inputs from VISp, the primary visual cortex, along with substantial inputs from various other cortical and visual thalamic regions. / FF and FB afferents showed similar cell-type selectivity, making stronger connections with looped neurons than with other projection types in layer (