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What resolves this contention: Conceptual conflict between the original rate-model framework and the later oscillatory/dynamic-systems framework for basal-ganglia pathophysiology; the SNr study reframes the apparent incompatibility as a unification rather than the original DeLong rate-only account. / The classical rate model and the oscillatory model are not incompatible; rate-model synaptic conditions induce bursting predicted by the oscillatory model in SNr neurons. / Hypokinetic and hyperkinetic disorders can be accounted for by specific firing-rate-based disturbances within the basal ganglia–thalamocortical motor circuit.
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May 16, 2026
Updated
May 17, 2026

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