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What resolves this contention: PV basket cell inhibition generates physiological ripples but its collapse generates pathological fast-ripples - functionally opposite roles of the same cell type / PV+ basket cells are necessary and sufficient for physiological ripple oscillation generation through synchronized inhibition / Pathological fast-ripples emerge specifically when perisomatic inhibition from PV+ basket cells collapses, not when it is active
Asked
May 16, 2026
Updated
May 17, 2026

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