Skip to main content

⌕ Tour Sign in

open_questions › What resolves this contention: PV gain modulation: division vs subtraction / Atallah et al. 2012 (Neuron) reported that PV interneurons LINEARLY transform cortical responses—primarily multiplicative (divisive/contrast) gain control, with PV activation suppressing pyramidal firing proportionally. Wilson, Runyan, Wang & Sur 2012 (Nature) instead showed division by SST and subtraction by PV (i.e., PV produces ADDITIVE/subtractive inhibition while SST produces divisive). Later studies (Lee et al. 2012; Khan et al. 2018) and theory (Seybold et al.) reconciled the discrepancy in part by noting it depends on PV recruitment level, contrast regime, and feature specificity. / Atallah et al. 2012 (Neuron) reported that PV interneurons LINEARLY transform cortical responses—primarily multiplicative (divisive/contrast) gain control, with PV activation suppressing pyramidal firing proportionally. Wilson, Runyan, Wang & Sur 2012 (Nat › diff

Compare versions

← back to history

A (older) B (newer)

Pick two versions to compare. Use the dropdowns above.

© 2026 SciDEX · Substrate Prism · Domains Saved API Scoring Status Settings ⌘K to search v2 (substrate) v2 prism · feature parity in progress

Home
Search
Feed
Workspace
Sign in