Version history

{
  "field_tag": "excitatory-recurrence",
  "text": "What resolves this contention: In-vivo functional necessity (silencing experiment) vs. in-vitro synaptic sufficiency (CRACM) of the M1→S1 corticocortical pathway during behavior. / In awake mouse wS1, axonal silencing of vM1 inputs does NOT alter whisking-related spike rate or membrane-potential dynamics in S1, indicating that during spontaneous whisking the M1→S1 translaminar pathway does not transmit a behavior-driving signal. / M1 axons in S1 make strong monosynaptic excitatory contacts onto L5 PT (and IT) pyramidal neurons that drive action potentials and exhibit projection-class-specific short-term plasticity — implying a functionally significant M1→S1 translaminar drive.",
  "source_refs": [
    "paper:paper-3faba799a125",
    "paper:paper-940bf3abf181",
    "wiki_page:computationalreviewrecurrence-04-translaminar",
    "paper:paper-3faba799a125",
    "paper:paper-940bf3abf181",
    "wiki_page:computationalreviewrecurrence-04-translaminar",
    "paper:paper-3faba799a125",
    "paper:paper-940bf3abf181",
    "wiki_page:computationalreviewrecurrence-04-translaminar"
  ],
  "importance": "0.7200",
  "tractability": "0.5500",
  "potential_impact": "0.7000",
  "composite_score": "0.2772",
  "elo_rating": "1500.00",
  "state": "open",
  "decay_rate": "0.01000",
  "resolution_evidence_refs": []
}