Version history

{
  "field_tag": "excitatory-recurrence",
  "text": "What resolves this contention: Different bottleneck identification for the GEVI field: one paper identifies a multi-parameter trade-off among near-infrared indicators, the other identifies a 2P excitation-mode failure of FRET-opsin GEVIs that can be circumvented by photocycle-aware illumination. The two limits coexist but emphasize different obstacles to scalable voltage imaging. / Neither GEVI characterized here surpasses in all three key parameters (brightness, kinetics, and sensitivity), so there is no unequivocal preference for one of the two. / However, the voltage sensitivity of most FRET-opsin GEVIs has been reported to decrease or vanish under two-photon (2P) excitation.",
  "source_refs": [
    "paper:paper-0b455d0a9412",
    "paper:paper-2481de1c0ae2",
    "wiki_page:computationalreviewrecurrence-16-synthesis",
    "paper:paper-0b455d0a9412",
    "paper:paper-2481de1c0ae2",
    "wiki_page:computationalreviewrecurrence-16-synthesis",
    "paper:paper-0b455d0a9412",
    "paper:paper-2481de1c0ae2",
    "wiki_page:computationalreviewrecurrence-16-synthesis"
  ],
  "importance": "0.7200",
  "tractability": "0.5500",
  "potential_impact": "0.7000",
  "composite_score": "0.2772",
  "elo_rating": "1500.00",
  "state": "open",
  "decay_rate": "0.01000",
  "resolution_evidence_refs": []
}