Version history

{
  "field_tag": "excitatory-recurrence",
  "text": "What resolves this contention: Kasthuri 2015 concludes that physical proximity is insufficient to predict whether two neurons form synapses, while Ding 2025 finds that axon–dendrite co-travel (a finer-grained proxy for opportunity) is itself a graded function of functional similarity. The two studies disagree on whether the opportunity-controlled signal in Peters' rule contains additional functional information; they use different graining of opportunity (every spine vs. ADP). / For example, by tracing the trajectories of all excitatory axons and noting their juxtapositions, both synaptic and non-synaptic, with every dendritic spine we refute the idea that physical proximity is sufficient to predict synaptic connectivity (the so-called Peters' rule). / Among pairs of neurons with at least one ADP, axon–dendrite co-travelling for longer-than-average distances was associated with higher-than-average feature similarity (",
  "source_refs": [
    "paper:paper-117c0465999e",
    "paper:paper-7ac22819c082",
    "wiki_page:computationalreviewrecurrence-06-connectomic-micons",
    "paper:paper-117c0465999e",
    "paper:paper-7ac22819c082",
    "wiki_page:computationalreviewrecurrence-06-connectomic-micons",
    "paper:paper-117c0465999e",
    "paper:paper-7ac22819c082",
    "wiki_page:computationalreviewrecurrence-06-connectomic-micons"
  ],
  "importance": "0.7200",
  "tractability": "0.5500",
  "potential_impact": "0.7000",
  "composite_score": "0.2772",
  "elo_rating": "1500.00",
  "state": "open",
  "decay_rate": "0.01000",
  "resolution_evidence_refs": []
}