Version history

{
  "field_tag": "excitatory-recurrence",
  "text": "What resolves this contention: Sign of the net L4→L5 effect in vivo (suppression via translaminar inhibition vs. expectation of net excitation from monosynaptic E→E paired-recording data); methodology and behavioral state differ. / In awake mouse S1, optogenetic activation of L4 directly SUPPRESSES L5 firing via deep fast-spiking inhibition, sharpening L5 spatial representations — at odds with a purely excitatory L4→L5 feedforward path. / In mouse C2 barrel column paired recordings, L4 excitatory neurons provide the strongest excitatory influence on the column, including direct E→E input to L5 — supporting a primarily excitatory L4-driven feedforward microcircuit.",
  "source_refs": [
    "paper:paper-bd34abdc91c9",
    "paper:paper-bdc020492b80",
    "wiki_page:computationalreviewrecurrence-04-translaminar",
    "paper:paper-bd34abdc91c9",
    "paper:paper-bdc020492b80",
    "wiki_page:computationalreviewrecurrence-04-translaminar",
    "paper:paper-bd34abdc91c9",
    "paper:paper-bdc020492b80",
    "wiki_page:computationalreviewrecurrence-04-translaminar"
  ],
  "importance": "0.7200",
  "tractability": "0.5500",
  "potential_impact": "0.7000",
  "composite_score": "0.2772",
  "elo_rating": "1500.00",
  "state": "open",
  "decay_rate": "0.01000",
  "resolution_evidence_refs": []
}