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open_questions › What resolves this contention: Bock 2011 concludes that E→I convergence in mouse V1 is non-selective with respect to orientation, while Lee 2016 (same EM platform but E→E network) reports strong orientation-based preference among excitatory pyramidal pairs. The studies do not contradict each other once cell-type identity is fixed (E→I vs E→E), but they jointly imply that wiring rules depend critically on the postsynaptic class — a fact often elided in network models. / In particular, we tested a prediction from recent physiological work–, cf.,: that inhibitory interneurons in the mouse primary visual cortex receive dense, convergent input from nearby excitatory (pyramidal) neurons with widely varying preferred stimulus orientations (). / Therefore, the preferential connectivity (, red versus blue line,< 0.05, red versus black line,< 0.05, Permutation tests; and 2f,< 0.05, Cochran–Armitage test) between neurons with si › diff

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