Version history

1 version on record. Newest first; the live version sits at the top with a live indicator.

  1. Live 7b375eb36e56
    5/17/2026, 4:35:28 PM
    Content snapshot 
    {
  "field_tag": "neuroscience",
  "text": "What resolves this contention: Histone modifications (especially H3 acetylation) at specific gene promoters persist for weeks after drug exposure and causally drive behavioral sensitization and reward / Many reported epigenetic changes are transient and may reflect ongoing transcriptional activity rather than stable epigenetic memory; the causal link often relies on pharmacological HDAC inhibitors with poor specificity",
  "source_refs": [
    "wiki_page:computationalreviewaddiction-03",
    "wiki_page:computationalreviewaddiction-03",
    "wiki_page:computationalreviewaddiction-03"
  ],
  "importance": "0.7200",
  "tractability": "0.5500",
  "potential_impact": "0.7000",
  "composite_score": "0.2772",
  "elo_rating": "1500.00",
  "state": "open",
  "decay_rate": "0.01000",
  "resolution_evidence_refs": []
}