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open_questions › What resolves this contention: {'position': 'Desensitization-induced receptor upregulation is the primary driver of nicotine dependence', 'supporting_dois': ['10.1016/j.bbr.2017.02.029', '10.3389/fnins.2025.1670883', '10.1111/ejn.70352'], 'cite_keys': []} / {'position': 'Desensitization is a complex process with subtype-specific effects that can be both pro-addictive and potentially therapeutic', 'supporting_dois': ['10.1016/j.alcohol.2009.09.027', '10.1016/j.pbb.2011.07.001', '10.1016/j.ejmech.2026.118679'], 'cite_keys': []} › diff

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