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What resolves this contention: Tension between continuum vs discrete-type accounts of cortical neurons. Excitatory morphological diversity in MICrONS reads as continuous, while inhibitory Sst neurons appear discretely separable into MET-types with type-specific connectivity. The conflict cuts across E vs I; the question whether E→E claims should rest on discrete excitatory categories remains open. / Contrary to previous classifications into discrete morphological types (m-types), our data-driven approach suggests that the morphological landscape of cortical excitatory neurons is better described as a continuum, with a few notable exceptions in layers 5 and 6. / We further analysed Martinotti cells-a somatostatin (Sst)-positive<sup>17</sup> morphological cell type<sup>18,19</sup>-which were classified successfully into Sst MET-types with distinct axon myelination and synaptic output connectivity patterns.
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May 16, 2026
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May 17, 2026

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