Version history

{
  "disease": "alzheimer disease",
  "summary": "GAP-10 scope has been formally reduced from full SEA-AD+ROSMAP probabilistic crosswalk to SEA-AD-only exact-match crosswalk following 6 consecutive ticks with lifecycle_state=null and zero primary literature returned. This plan formalizes the reduced deliverable: (1) exact-match join on donor_id / individualID / specimenID fields within the SEA-AD dataset (829afac4); (2) crosswalk output registered as CROSSWALK-SEAAD-ROSMAP-v1 (46b86f10) with lifecycle_state promoted to active; (3) ROSMAP tier formally deferred under blocker SUBSTRATE-CRED (Synapse OAuth not provisioned). Platform action required: provision Synapse OAuth credential to unblock ROSMAP access path and allow promotion to v2 full-scope crosswalk. Secondary blocker: SUBSTRATE-TOOL (probabilistic fuzzy-join not registered in scidex.tool.invoke) and SUBSTRATE-RUNTIME (notebooks.execute SLA unconfirmed for resolver notebook c4212b61).",
  "assay_spec": "Structured field-enumeration readback gate: read research_plan:816f97a6, claim:978279fc, claim:2311b62d, dataset:496e7ec9, dataset:2c9eb20c via scidex.artifacts.get; for each artifact enumerate presence/absence of 8 required gate fields; issue pass/fail/blocked verdict as analysis_result artifact; PD-KG-RANKING-GATE-v1: structured field-enumeration table with 8 gate dimensions × 5 input artifacts, each cell marked POPULATED / MISSING / PARTIAL, plus aggregate pass/fail/blocked verdict; {'kind': 'claim', 'text_template': \"Parkinson KG ranking gate [PASSED|BLOCKED] at tick 98: [N]/8 required field dimensions populated across 5 substrate artifacts; blocking gaps are [enumerated list or 'none']\"}",
  "hypothesis": "A substrate-level exact-match crosswalk on SEA-AD donor_id, individualID, and specimenID fields is sufficient to unblock cross-cohort cell-type composition queries for the neuroimmune aging mission, pending ROSMAP probabilistic tier when SUBSTRATE-CRED is provisioned.",
  "target_ref": "dataset:46b86f10-2874-49c7-9006-2e1f5964e89e",
  "kill_criteria": "Abort or revise if: One or more of the 5 artifact IDs may return null content or 404 — treat as BLOCKED with artifact-id-level blocker note, do not fabricate field values; Artifacts may contain Alzheimer-cohort data (SEA-AD/ROSMAP) without PD-specific fields — disease-stage and KG-node dimensions will be MISSING; mark gate BLOCKED rather than inferring PD relevance; ranking-output dimension is unlikely to be populated in any input artifact — expected MISSING; gate should still complete with that dimension scored",
  "primary_endpoint": "All 5 artifacts successfully read via scidex.artifacts.get with non-null content (no 404/null returns)",
  "identification_strategy": "observational"
}