Version history

{
  "hypothesis": "Enhancer and plasmid designs should not be promoted as cell-type-specific tools until assay designs separate biological signal from batch, barcode, delivery, and readout noise.",
  "identification_strategy": "observational",
  "assay_spec": "Start from Bosiljka-related seed refs and local SciDEX artifacts. Extract construct design, delivery method, cell-type labels, controls, batch structure, readouts, and noise sources. Publish protocol-quality notes, data-management requirements, and wet-lab follow-up proposals.",
  "primary_endpoint": "A protocol audit table that flags controls, noise sources, construct constraints, data provenance, and validation-readiness per enhancer artifact.",
  "summary": "Bootstrap research plan for the enhancer-lab persona: inventory enhancer screening, plasmid construction, AAV delivery, single-cell, and spatial readout artifacts in SciDEX; then rank which protocols are ready for reuse or need clearer controls."
}