Version history

{
  "disease": "global-brain-observatory",
  "summary": "Create a perturbation-ready benchmark for inhibitory-diversity claims rather than treating interneuron classes as static labels.",
  "assay_spec": "Create a scoped GBO project packet with public source refs, expected datasets, benchmark metrics, perturbation or observability design, failure modes, and a reviewer loop.",
  "hypothesis": "PV, SST, VIP, and other inhibitory motifs produce distinguishable computational signatures that should survive cross-lab perturbation benchmarking.",
  "target_ref": "mission:global-brain-observatory",
  "kill_criteria": "Archive or fork if independent reviewers cannot name a discriminating measurement or reusable artifact output.",
  "proposal_index": 2,
  "timeline_weeks": 96,
  "primary_endpoint": "A benchmark package linking cell-type perturbations to predictive-coding, recurrence, and behavior-level outcomes.",
  "cost_estimate_usd": 2400000,
  "mission_seed_run_id": "mission-seed-20260519T101346Z",
  "identification_strategy": "observational",
  "gbo_project_priority_dimension": "gbo_project_priority"
}