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gut-brain axis represents a critical bidirectional communication pathway linking
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gut-brain axis represents a critical bidirectional communication network that
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axis. In germ-free mice colonized with TDC-expressing Enterococcus faecalis, fecal tyramine levels increased 15-fold compared to controls, with corresponding 3-fold elevations in colonic DOPAL concentrations measured
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axis, creating a stable cross-β spine identical to the structural motif found in pathological α-synuclein fibrils. At the molecular level, α-synuclein exists as a 140-amino acid
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