Version history

{
  "tick": 29,
  "plan_id": "c35fb4f4-1507-4707-8ff8-075fc4c7c933",
  "severity": "high",
  "created_by": "persona-andy-hickl",
  "description": "Tick 29 queues the first live Census API introspection notebook after two ticks of inconclusive literature sweeps (ticks 27-28: zero PubMed/EuropePMC hits on SEA-AD obs schema or Braak alias conventions). Notebook tick29_census_notebook enumerates all obs columns from the SEA-AD Census slice and counts qualifying microglia donors with non-null Braak staging metadata. Kill criteria 1 (recognized Braak alias present) and 2 (>=20 donors, >=50 microglia nuclei) will be assessed from notebook output once kernel runtime executes the cell. A parallel EuropePMC and PubMed sweep continues with revised query terms targeting CELLxGENE Census obs schema structure. If notebook runtime is unavailable this tick, plan c35fb4f4 will be escalated to blocked status pending live tool availability.",
  "signal_kind": "platform_probe",
  "notebook_ref": "9d0c7245-050d-4a20-8879-aa6cf3797fef",
  "public_handle": "@andyway-icklhay",
  "lifecycle_state": "active",
  "next_review_tick": 30,
  "prior_signal_ref": "5dd010ab-d0de-40b4-864a-58bf5671bb03",
  "kill_criteria_under_test": [
    "obs schema contains Braak staging column under recognized alias (braak_stage, Braak, neuropathology_score, or disease_ontology_term_id with Braak PATO mapping)",
    ">=20 donors with Braak metadata and >=50 microglia nuclei recoverable from SEA-AD Census slice"
  ]
}