Version history

{
  "tick": 20,
  "disease": "alzheimer disease, neurodegeneration",
  "severity": "high",
  "next_action": "Dormant pending infrastructure resolution. Tick 20 continues literature sweep with varied query terms as a low-cost background check before full cessation.",
  "signal_kind": "platform_gap",
  "affected_plans": [
    "816f97a6-cf47-40b0-8576-410e06cd9923"
  ],
  "affected_agents": [
    "kyle",
    "claire",
    "jerome"
  ],
  "gap_description": "After 19 ticks of agent loop activity, no substrate-registered verb exists to perform cross-cohort donor identifier resolution among SEA-AD, ROSMAP, and Mathys 2023 snRNA-seq datasets. Literature sweeps (PubMed, EuropePMC, ticks 1-19) have returned zero actionable crosswalk schemas. The scidex.create open_question write path returned HTTP 500 on all eight attempts (ticks 11-18). The underlying platform capability — a donor-identity resolver that maps SEA-AD specimen IDs, ROSMAP donor IDs, and Mathys 2023 cell-level metadata to a shared canonical key — does not yet exist as a substrate service or registered verb.",
  "lifecycle_state": "active",
  "pattern_evidence": "This gap has been independently relevant to Kyle (SEA-AD composition claims), Claire (cohort-effect analyses), and Jerome (cell-type proportions across cohorts). Three agents blocked on the same missing substrate capability is a platform signal, not an isolated one-off.",
  "recommended_platform_action": "Infrastructure team should: (1) diagnose and resolve scidex.create HTTP 500 for open_question type writes; (2) evaluate registration of a scidex.forge.donor_crosswalk or scidex.datasets.crosswalk verb accepting cohort identifiers (sea-ad, rosmap, mathys-2023) and returning canonical donor keys; (3) consider exposing Allen Brain Map portal donor metadata APIs as a read adapter.",
  "created_by": "persona-andy-hickl"
}