Version history

{
  "kind": "infographic",
  "prompt": "Research coverage: Publication counts by neuromodulator × brain region (2010-2026)",
  "provider": "other",
  "raw_fields": {
    "unit": "publication count",
    "papers": [
      {
        "doi": "pubmed_count_query",
        "label": "dopamine × prefrontal cortex",
        "value": 3344,
        "n_analyzed": 3344,
        "n_definition": "publication count from PubMed",
        "scope_region": "prefrontal cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying dopamine in prefrontal cortex",
        "value_source_sentence": "PubMed search 'dopamine AND prefrontal cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 3344 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "dopamine × visual cortex",
        "value": 224,
        "n_analyzed": 224,
        "n_definition": "publication count from PubMed",
        "scope_region": "visual cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying dopamine in visual cortex",
        "value_source_sentence": "PubMed search 'dopamine AND visual cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 224 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "dopamine × hippocampus",
        "value": 2621,
        "n_analyzed": 2621,
        "n_definition": "publication count from PubMed",
        "scope_region": "hippocampus",
        "taxonomic_level": "all species",
        "scope_population": "publications studying dopamine in hippocampus",
        "value_source_sentence": "PubMed search 'dopamine AND hippocampus AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 2621 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "dopamine × amygdala",
        "value": 1116,
        "n_analyzed": 1116,
        "n_definition": "publication count from PubMed",
        "scope_region": "amygdala",
        "taxonomic_level": "all species",
        "scope_population": "publications studying dopamine in amygdala",
        "value_source_sentence": "PubMed search 'dopamine AND amygdala AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 1116 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "dopamine × striatum",
        "value": 11002,
        "n_analyzed": 11002,
        "n_definition": "publication count from PubMed",
        "scope_region": "striatum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying dopamine in striatum",
        "value_source_sentence": "PubMed search 'dopamine AND striatum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 11002 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "dopamine × cerebellum",
        "value": 529,
        "n_analyzed": 529,
        "n_definition": "publication count from PubMed",
        "scope_region": "cerebellum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying dopamine in cerebellum",
        "value_source_sentence": "PubMed search 'dopamine AND cerebellum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 529 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "serotonin × prefrontal cortex",
        "value": 1902,
        "n_analyzed": 1902,
        "n_definition": "publication count from PubMed",
        "scope_region": "prefrontal cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying serotonin in prefrontal cortex",
        "value_source_sentence": "PubMed search 'serotonin AND prefrontal cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 1902 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "serotonin × visual cortex",
        "value": 149,
        "n_analyzed": 149,
        "n_definition": "publication count from PubMed",
        "scope_region": "visual cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying serotonin in visual cortex",
        "value_source_sentence": "PubMed search 'serotonin AND visual cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 149 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "serotonin × hippocampus",
        "value": 2934,
        "n_analyzed": 2934,
        "n_definition": "publication count from PubMed",
        "scope_region": "hippocampus",
        "taxonomic_level": "all species",
        "scope_population": "publications studying serotonin in hippocampus",
        "value_source_sentence": "PubMed search 'serotonin AND hippocampus AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 2934 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "serotonin × amygdala",
        "value": 1010,
        "n_analyzed": 1010,
        "n_definition": "publication count from PubMed",
        "scope_region": "amygdala",
        "taxonomic_level": "all species",
        "scope_population": "publications studying serotonin in amygdala",
        "value_source_sentence": "PubMed search 'serotonin AND amygdala AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 1010 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "serotonin × striatum",
        "value": 1626,
        "n_analyzed": 1626,
        "n_definition": "publication count from PubMed",
        "scope_region": "striatum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying serotonin in striatum",
        "value_source_sentence": "PubMed search 'serotonin AND striatum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 1626 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "serotonin × cerebellum",
        "value": 326,
        "n_analyzed": 326,
        "n_definition": "publication count from PubMed",
        "scope_region": "cerebellum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying serotonin in cerebellum",
        "value_source_sentence": "PubMed search 'serotonin AND cerebellum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 326 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "acetylcholine × prefrontal cortex",
        "value": 523,
        "n_analyzed": 523,
        "n_definition": "publication count from PubMed",
        "scope_region": "prefrontal cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying acetylcholine in prefrontal cortex",
        "value_source_sentence": "PubMed search 'acetylcholine AND prefrontal cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 523 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "acetylcholine × visual cortex",
        "value": 165,
        "n_analyzed": 165,
        "n_definition": "publication count from PubMed",
        "scope_region": "visual cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying acetylcholine in visual cortex",
        "value_source_sentence": "PubMed search 'acetylcholine AND visual cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 165 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "acetylcholine × hippocampus",
        "value": 1624,
        "n_analyzed": 1624,
        "n_definition": "publication count from PubMed",
        "scope_region": "hippocampus",
        "taxonomic_level": "all species",
        "scope_population": "publications studying acetylcholine in hippocampus",
        "value_source_sentence": "PubMed search 'acetylcholine AND hippocampus AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 1624 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "acetylcholine × amygdala",
        "value": 192,
        "n_analyzed": 192,
        "n_definition": "publication count from PubMed",
        "scope_region": "amygdala",
        "taxonomic_level": "all species",
        "scope_population": "publications studying acetylcholine in amygdala",
        "value_source_sentence": "PubMed search 'acetylcholine AND amygdala AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 192 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "acetylcholine × striatum",
        "value": 830,
        "n_analyzed": 830,
        "n_definition": "publication count from PubMed",
        "scope_region": "striatum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying acetylcholine in striatum",
        "value_source_sentence": "PubMed search 'acetylcholine AND striatum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 830 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "acetylcholine × cerebellum",
        "value": 148,
        "n_analyzed": 148,
        "n_definition": "publication count from PubMed",
        "scope_region": "cerebellum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying acetylcholine in cerebellum",
        "value_source_sentence": "PubMed search 'acetylcholine AND cerebellum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 148 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "norepinephrine × prefrontal cortex",
        "value": 886,
        "n_analyzed": 886,
        "n_definition": "publication count from PubMed",
        "scope_region": "prefrontal cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying norepinephrine in prefrontal cortex",
        "value_source_sentence": "PubMed search 'norepinephrine AND prefrontal cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 886 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "norepinephrine × visual cortex",
        "value": 85,
        "n_analyzed": 85,
        "n_definition": "publication count from PubMed",
        "scope_region": "visual cortex",
        "taxonomic_level": "all species",
        "scope_population": "publications studying norepinephrine in visual cortex",
        "value_source_sentence": "PubMed search 'norepinephrine AND visual cortex AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 85 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "norepinephrine × hippocampus",
        "value": 1182,
        "n_analyzed": 1182,
        "n_definition": "publication count from PubMed",
        "scope_region": "hippocampus",
        "taxonomic_level": "all species",
        "scope_population": "publications studying norepinephrine in hippocampus",
        "value_source_sentence": "PubMed search 'norepinephrine AND hippocampus AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 1182 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "norepinephrine × amygdala",
        "value": 465,
        "n_analyzed": 465,
        "n_definition": "publication count from PubMed",
        "scope_region": "amygdala",
        "taxonomic_level": "all species",
        "scope_population": "publications studying norepinephrine in amygdala",
        "value_source_sentence": "PubMed search 'norepinephrine AND amygdala AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 465 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "norepinephrine × striatum",
        "value": 668,
        "n_analyzed": 668,
        "n_definition": "publication count from PubMed",
        "scope_region": "striatum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying norepinephrine in striatum",
        "value_source_sentence": "PubMed search 'norepinephrine AND striatum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 668 results"
      },
      {
        "doi": "pubmed_count_query",
        "label": "norepinephrine × cerebellum",
        "value": 164,
        "n_analyzed": 164,
        "n_definition": "publication count from PubMed",
        "scope_region": "cerebellum",
        "taxonomic_level": "all species",
        "scope_population": "publications studying norepinephrine in cerebellum",
        "value_source_sentence": "PubMed search 'norepinephrine AND cerebellum AND (modulation OR neuromodulation) AND 2010:2026[dp]' returned 164 results"
      }
    ],
    "comparison_name": "Research coverage: Publication counts by neuromodulator × brain region (2010-2026)",
    "comparison_type": "research_gap_heatmap",
    "homogeneity_check": "All values are PubMed publication counts using the same query structure. Counts include all study types and species. Differences in count reflect genuine research attention gaps. Caveat: search terms may not capture all relevant papers (e.g., 'VTA' studies may not mention 'dopamine' explicitly). Counts are not normalized by total field output."
  },
  "section_id": "section_12_evidence",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation/blob/95db5c630fe54e183d9c452cf826ce502d4a872d/evidence/section_12_evidence.json",
  "target_ref": "wiki_page:computationalreviewneuromodulation-12",
  "review_repo": "ComputationalReviewNeuromodulation",
  "section_ref": "wiki_page:computationalreviewneuromodulation-12",
  "source_path": "evidence/section_12_evidence.json",
  "source_refs": [],
  "section_title": "Synthesis and Evidence Assessment: What We Know, What We Think We Know, and What We Don't",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95db5c630fe54e183d9c452cf826ce502d4a872d",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation"
  },
  "generation_status": "complete",
  "review_bundle_ref": "analysis_bundle:ab-a3dbbaf9b625",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation/blob/95db5c630fe54e183d9c452cf826ce502d4a872d/evidence/section_12_evidence.json",
  "commit_sha": "95db5c630fe54e183d9c452cf826ce502d4a872d",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation"
}