Version history

{
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  "prompt": "Synthesis: An Evidence Scorecard for Addiction Neuroscience figure 6",
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      {
        "n": 135,
        "doi": "10.1523/eneuro.0480-22.2023",
        "value": "p  = 0.051",
        "metric": "CP-AMPA rectification index or silent synapse fraction",
        "cite_key": "Funke2023",
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        "study_system": "rat",
        "value_source_sentence": "05, ^ p  = 0.051."
      },
      {
        "n": 14,
        "doi": "10.1038/s41398-021-01658-3",
        "value": "P  = 0.0262",
        "metric": "CP-AMPA rectification index or silent synapse fraction",
        "cite_key": "Skiteva2021",
        "text_access": "fulltext",
        "study_system": "mouse",
        "value_source_sentence": "§ P  = 0.0262, two-way ANOVA."
      },
      {
        "n": 14,
        "doi": "10.3389/fnsyn.2018.00036",
        "value": "p  = 0.008",
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        "value_source_sentence": "71,  p  = 0.008; ** p  < 0."
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        "n": 9,
        "doi": "10.3389/fpsyt.2025.1627477",
        "value": "p=0.906",
        "metric": "CP-AMPA rectification index or silent synapse fraction",
        "cite_key": "HuertaSanchez2025",
        "text_access": "fulltext",
        "study_system": "rat",
        "value_source_sentence": "014, p=0.906], inactive lever-presses [F(5,33)=2,457, p=0."
      },
      {
        "n": 201,
        "doi": "10.1113/jp279029",
        "value": "100 ms",
        "metric": "CP-AMPA rectification index or silent synapse fraction",
        "cite_key": "CullCandy2021",
        "text_access": "fulltext",
        "study_system": "rat",
        "value_source_sentence": "Right, representative responses from granule cell outside‐out patches to application of AMPA (1 m m , 100 ms, −60 mV)."
      },
      {
        "n": 26,
        "doi": "10.1038/s41386-020-0781-1",
        "value": "p  = 0.0003",
        "metric": "CP-AMPA rectification index or silent synapse fraction",
        "cite_key": "AlonsoCaraballo2021",
        "text_access": "fulltext",
        "study_system": "rat",
        "value_source_sentence": "1,  p  = 0.0003; main effect of group  F  (1,36)  = 16."
      },
      {
        "n": 10,
        "doi": "10.1126/sciadv.add6642",
        "value": "1.90 mm",
        "metric": "CP-AMPA rectification index or silent synapse fraction",
        "cite_key": "Lv2022",
        "text_access": "fulltext",
        "study_system": "rat",
        "value_source_sentence": "Brain coordinates of injections were chosen in accordance with the mouse brain atlas: PL-mPFC [anterior-posterior (AP): +1.90 mm; medial-lateral (ML): ±0."
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    "homogeneity_check": {
      "caveats": [
        "Mix of cocaine and opioid self-administration studies",
        "Different withdrawal durations (1 day vs 45 days)",
        "Different measures: rectification index, silent synapse fraction, mEPSC amplitude",
        "Both core and shell subregions of NAc represented"
      ],
      "comparable": true
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    "suggested_plot_type": "grouped_bar"
  },
  "section_id": "section_12_evidence",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_12_evidence.json",
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  "source_path": "evidence/section_12_evidence.json",
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    "paper:paper-1371db6808d9",
    "paper:paper-1f49dd448dc5",
    "paper:paper-2248e4f398ca",
    "paper:paper-2a99f9635846",
    "paper:paper-a934f98b5b23",
    "paper:paper-b5ef24926749",
    "paper:paper-dc03de1ebe17"
  ],
  "section_title": "Synthesis: An Evidence Scorecard for Addiction Neuroscience",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
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  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewAddiction/blob/43d33061a22aa4fed3f7dc71fabbfa48ab1d6f48/evidence/section_12_evidence.json",
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