Version history

{
  "kind": "infographic",
  "prompt": "VIP disinhibitory circuit latencies across cortical areas",
  "provider": "other",
  "raw_fields": {
    "title": "VIP disinhibitory circuit latencies across cortical areas",
    "papers": [
      {
        "n": null,
        "doi": "10.1038/nature12676",
        "value": "VIP activation latency: ACx 2.5±0.22ms, mPFC 1.3±0.40ms; Inhibition trough: ACx 10ms, mPFC 7ms",
        "cite_key": "Pi2013",
        "study_system": "mouse auditory and medial prefrontal cortex",
        "value_source_sentence": "The first group of neurons was strongly activated at a very low latency (ACx: 2.5±0.22ms, mPFC: 1.3±0.40ms), with low jitter (ACx: 1.4±0.21, mPFC: 1.1±0.10ms)."
      },
      {
        "n": null,
        "doi": "10.1016/j.neuron.2022.10.036",
        "value": "VIP activation linearly scales gamma power locally",
        "cite_key": "Veit2023",
        "study_system": "mouse V1 in vivo",
        "value_source_sentence": "VIP disinhibitory interneurons in mouse cortex linearly scale gamma power locally without changing its stimulus tuning."
      }
    ],
    "figure_id": "fig_vip_disinhibition_latency",
    "n_analyzed": "varies by study",
    "description": "Comparison of VIP-mediated disinhibition timing across studies and cortical areas",
    "n_definition": "neurons recorded",
    "scope_region": "mouse cortex (ACx, mPFC, V1)",
    "comparison_type": "cross_study_quantitative",
    "taxonomic_level": "cell type (VIP)",
    "scope_population": "VIP interneurons and their downstream targets",
    "homogeneity_check": "Limited comparability. Different cortical areas, different measures (spike latency vs gamma power). The VIP disinhibitory motif appears conserved but its functional readout differs by area."
  },
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  "source_refs": [
    "paper:paper-065a0eae69a5",
    "paper:paper-d895aafe5d83"
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  "section_title": "Cell-Type-Specific Inhibition in Cortical Processing",
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}