Details

kind
infographic
prompt
Modeling Inhibitory Diversity figure 2
provider
other
section_id
section_12_evidence
source_url
https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory/blob/934e0675cc6d5ffd9978a4a9883b31166ce000e2/evidence/section_12_evidence.json
target_ref
wiki_page:computationreviewinhibitory-12
review_repo
ComputationReviewInhibitory
section_ref
wiki_page:computationreviewinhibitory-12
source_path
evidence/section_12_evidence.json
section_title
Modeling Inhibitory Diversity
generation_status
complete
review_bundle_ref
analysis_bundle:ab-5fc3c0c0505b
origin_url
https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory/blob/934e0675cc6d5ffd9978a4a9883b31166ce000e2/evidence/section_12_evidence.json
commit_sha
934e0675cc6d5ffd9978a4a9883b31166ce000e2
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory
Raw fields (3)
raw_fields
{
  "papers": [
    {
      "doi": "10.3389/frai.2025.1654716",
      "value": null,
      "cite_key": "Chavez-Autor2025",
      "value_source_sentence": "This conceptual analysis (i) formalizes <i>novelty</i>, <i>usefulness</i>, and <i>diversity</i> with operational definitions; (ii) develops multiple gain-update policies (exponential, linear, logistic) with stability constraints and sensitivity expectations; (iii) derives falsifiable behavioral indi"
    },
    {
      "doi": "10.3389/fnetp.2025.1589566",
      "value": null,
      "cite_key": "Dimulescu2025",
      "value_source_sentence": "Overall, our results demonstrate that the coarse-grained dynamics is robust to changes in both model type and network resolution."
    },
    {
      "doi": "10.1101/2025.05.14.654005",
      "value": null,
      "cite_key": "Veneto2025",
      "value_source_sentence": "Our results reveal that, in the absence of excitatory scaling, PV-to-E scaling can effectively compensate and rescue memory specificity, highlighting the presence of degenerate mechanisms in the brain."
    },
    {
      "doi": "10.1371/journal.pbio.3003451",
      "value": null,
      "cite_key": "Schulz2025",
      "value_source_sentence": "Our analysis of T1 MRI data from 46,381 UK Biobank participants reveals that simpler machine learning models, and notably those with excessive regularization, demonstrate superior sensitivity to disease-relevant changes compared to their more complex counterparts, despite being less accurate in chro"
    },
    {
      "doi": "10.1101/2025.09.16.676508",
      "value": "qualitative - variable parameters, stable output",
      "cite_key": null,
      "value_source_sentence": "<h4>Summary</h4>  Neural circuits are composed of different neuron types that exhibit distinctly different computational properties resulting from the sets of ion channels expressed. Profound insight exists into how neural computations arise from the precise regulation of ion channels (Armstrong et "
    }
  ],
  "description": "Comparison of parameter degeneracy findings across different model systems, showing that many parameter combinations produce similar dynamics",
  "n_definition": "number of parameter sets tested",
  "comparison_type": "parameter_degeneracy",
  "taxonomic_level": "N/A - computational",
  "comparison_title": "Parameter sensitivity and degeneracy across neural circuit models",
  "homogeneity_check": "Studies use different model organisms and circuit types. Degeneracy appears to be a general principle but the degree varies with model complexity."
}
source_refs
[
  "paper:paper-09e846185ab4",
  "paper:paper-6ccfa74ffbae",
  "paper:paper-a2d24b27cf1f",
  "paper:paper-dbc3d39a0f91",
  "paper:paper-ea47e26b1a66"
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "934e0675cc6d5ffd9978a4a9883b31166ce000e2",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory"
}

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