Details

kind
infographic
prompt
SST contribution to surround suppression across studies
provider
other
section_id
section_05_evidence
source_url
https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory/blob/934e0675cc6d5ffd9978a4a9883b31166ce000e2/evidence/section_05_evidence.json
target_ref
wiki_page:computationreviewinhibitory-05
review_repo
ComputationReviewInhibitory
section_ref
wiki_page:computationreviewinhibitory-05
source_path
evidence/section_05_evidence.json
section_title
SST Interneuron Function
generation_status
complete
review_bundle_ref
analysis_bundle:ab-5fc3c0c0505b
origin_url
https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory/blob/934e0675cc6d5ffd9978a4a9883b31166ce000e2/evidence/section_05_evidence.json
commit_sha
934e0675cc6d5ffd9978a4a9883b31166ce000e2
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory
Raw fields (3)
raw_fields
{
  "metric": "Surround suppression index change with SST manipulation",
  "papers": [
    {
      "n": 0,
      "doi": "10.3389/fncir.2015.00060",
      "value": "70  mV",
      "cite_key": "Krishnamurthy2015",
      "study_system": "mouse",
      "value_source_sentence": "Parameter  Pyramidal  Basket  Martinotti  Unit      E leak   −70  −70  −70  mV    E Na   50  50  50  mV    E K   −100  −100  −100  mV    g leak   0.0001  0.00015  0.00015  S/cm 2     g Na   0.05  0.05  0.05  S/cm 2     g K   0.005  0.01  0.01  S/cm 2     g M   7e−5  0.000098  0.0001  S/cm 2     Soma"
    },
    {
      "n": 5,
      "doi": "10.1371/journal.pcbi.1010861",
      "value": "500 ms",
      "cite_key": "Gilday2023",
      "study_system": "mouse",
      "value_source_sentence": "Scale bars—150 spikes/sec, and 500 ms."
    },
    {
      "n": 1,
      "doi": "10.3389/fncir.2012.00043",
      "value": "100 Hz",
      "cite_key": "Sachdev2012",
      "study_system": "rat",
      "value_source_sentence": "These fluctuations are dominated by inhibition at frequencies between approximately 2 and 100 Hz (Cowan and Wilson,  1994 ; Hasenstaub et al.,  2005 ) and the membrane potential of single neurons is dominated by inhibition (Rudolph et al.,  2007 )."
    }
  ],
  "section": "5.2",
  "n_analyzed": "varies by study",
  "n_definition": "neurons recorded during size tuning experiments",
  "scope_region": "primary visual cortex (V1)",
  "comparison_name": "SST contribution to surround suppression across studies",
  "taxonomic_level": "N/A",
  "scope_population": "orientation-tuned pyramidal neurons",
  "homogeneity_check": "CAUTION: Studies differ in whether SST cells were activated vs silenced, stimulus parameters (spatial frequency, contrast), and how surround suppression index was calculated. Some used gratings, others noise stimuli."
}
source_refs
[
  "paper:paper-7cf52a12f6e4",
  "paper:paper-8e032153c1c2",
  "paper:paper-e27904276d7a"
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "934e0675cc6d5ffd9978a4a9883b31166ce000e2",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationReviewInhibitory"
}

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