Version history

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  1. Live 87e4271524c1
    5/17/2026, 4:35:28 PM
    Content snapshot
    {
      "kind": "infographic",
      "prompt": "Computational Framework Coverage Across Neuromodulators",
      "provider": "other",
      "raw_fields": {
        "title": "Computational Framework Coverage Across Neuromodulators",
        "metric": "Number of distinct computational models with empirical validation",
        "papers": [
          {
            "doi": "aggregate",
            "value": 27,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "DA-RL/RPE",
            "value_source_sentence": "Count of papers in our search matching 'DA-RL/RPE' criteria: 27"
          },
          {
            "doi": "aggregate",
            "value": 9,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "DA-precision/active_inference",
            "value_source_sentence": "Count of papers in our search matching 'DA-precision/active_inference' criteria: 9"
          },
          {
            "doi": "aggregate",
            "value": 19,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "NE-adaptive_gain",
            "value_source_sentence": "Count of papers in our search matching 'NE-adaptive_gain' criteria: 19"
          },
          {
            "doi": "aggregate",
            "value": 8,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "NE-uncertainty",
            "value_source_sentence": "Count of papers in our search matching 'NE-uncertainty' criteria: 8"
          },
          {
            "doi": "aggregate",
            "value": 21,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "NE-arousal_optimization",
            "value_source_sentence": "Count of papers in our search matching 'NE-arousal_optimization' criteria: 21"
          },
          {
            "doi": "aggregate",
            "value": 2,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "ACh-uncertainty",
            "value_source_sentence": "Count of papers in our search matching 'ACh-uncertainty' criteria: 2"
          },
          {
            "doi": "aggregate",
            "value": 9,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "ACh-attention",
            "value_source_sentence": "Count of papers in our search matching 'ACh-attention' criteria: 9"
          },
          {
            "doi": "aggregate",
            "value": 2,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "5HT-opponent",
            "value_source_sentence": "Count of papers in our search matching '5HT-opponent' criteria: 2"
          },
          {
            "doi": "aggregate",
            "value": 10,
            "condition": "Systematic search of computational neuromodulation literature",
            "framework": "Multi-modulator",
            "value_source_sentence": "Count of papers in our search matching 'Multi-modulator' criteria: 10"
          }
        ],
        "n_analyzed": "Based on systematic search of 150 papers",
        "description": "How many computational frameworks exist for each neuromodulator, and which frameworks have been validated with empirical data vs. remain purely theoretical",
        "n_definition": "Number of distinct published models per modulator-framework combination",
        "scope_region": "Brain-wide",
        "comparison_id": "fig_sec11_modulator_framework_coverage",
        "taxonomic_level": "Not applicable",
        "scope_population": "Computational neuroscience literature",
        "homogeneity_check": "Moderate homogeneity: all entries count published computational models, but 'empirical validation' ranges from fitting behavioral data to predicting neural firing patterns, creating heterogeneity in what counts as validated."
      },
      "section_id": "section_11_evidence",
      "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation/blob/95db5c630fe54e183d9c452cf826ce502d4a872d/evidence/section_11_evidence.json",
      "target_ref": "wiki_page:computationalreviewneuromodulation-11",
      "review_repo": "ComputationalReviewNeuromodulation",
      "section_ref": "wiki_page:computationalreviewneuromodulation-11",
      "source_path": "evidence/section_11_evidence.json",
      "source_refs": [],
      "section_title": "Computational Models of Brain-Wide Neuromodulation",
      "source_policy": {
        "mode": "public_source_pointer_with_short_context",
        "notes": [
          "Local review repositories are read-only inputs.",
          "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
        ],
        "source_commit_sha": "95db5c630fe54e183d9c452cf826ce502d4a872d",
        "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation"
      },
      "generation_status": "complete",
      "review_bundle_ref": "analysis_bundle:ab-a3dbbaf9b625",
      "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation/blob/95db5c630fe54e183d9c452cf826ce502d4a872d/evidence/section_11_evidence.json",
      "commit_sha": "95db5c630fe54e183d9c452cf826ce502d4a872d",
      "created_by": "persona-jerome-lecoq-gbo-neuroscience",
      "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewNeuromodulation"
    }