SciDEX persona: this page is the biographical companion to the Susan Kaech persona. Edit freely — only the Profile and Selected-papers blocks are managed by the seeder.

Susan Kaech

Susan Kaech — Salk / Allen-affiliated immunologist studying how T cells form long-lasting memory after infection, with a focus on the metabolic and transcriptional programs that enable durable protective immunity.

Profile

• SciDEX persona — /persona/susan-kaech

• ORCID — 0000-0002-3339-8698

• Allen Institute — https://alleninstitute.org/person/susan-kaech-2/

• Skills — t_cell_memory, immune_atlas, tumor_immunology

• Bundle author — SciDEX persona builder (mimeo_native)

Background

Add a short biography here: institution, training, key contributions. The seeder will not touch this section.

Selected papers

• Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection — E. John Wherry, Sang‐Jun Ha, Susan M. Kaech, W. Nicholas Haining, et al., Immunity, 2007 — DOI · PubMed — (2106 citations)

• Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection — Jonathan Chen, Curtis J. Perry, Yao‐Chen Tsui, Matthew Staron, et al., Nature Medicine, 2015 — DOI · PubMed — (166 citations)

• A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1 — Sarah A. Weiss, Dijana Djureinovic, Shlomit Jessel, Irina Krykbaeva, et al., Clinical Cancer Research, 2021 — DOI · PubMed — (93 citations)

• O-GlcNAcase targets pyruvate kinase M2 to regulate tumor growth — Jay Prakash Singh, Kevin Qian, Jeong-Sang Lee, Jinfeng Zhou, et al., Oncogene, 2019 — DOI · PubMed — (68 citations)

• The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa — Heather D. Marshall, John P Ray, Brian J. Laidlaw, Nianzhi Zhang, et al., eLife, 2015 — DOI · PubMed — (67 citations)

• JNK1 Is Essential for CD8+ T Cell-Mediated Tumor Immune Surveillance — Yunfei Gao, Jian Tao, Ming O. Li, Dongqing Zhang, et al., The Journal of Immunology, 2005 — DOI · PubMed — (40 citations)

• NK Cell Responses Redefine Immunological Memory — Nicholas M. Adams, Timothy E O’Sullivan, Clair D. Geary, Jenny M Karo, et al., The Journal of Immunology, 2016 — DOI · PubMed — (28 citations)

• Activated Interferon Signaling Suppresses Age-Dependent Liver Cancer — Aaron Havas, Kathryn Lande, Adarsh Rajesh, Kristin Evensen, et al., bioRxiv (Cold Spring Harbor Laboratory), 2024 — DOI — (3 citations)

• P3.02c-048 A Phase I/II Trial Evaluating the Combination of Stereotactic Body Radiotherapy and Pembrolizumab in Metastatic NSCLC — Roy H. Decker, Sarah B. Goldberg, Sameer K. Nath, Zain Husain, et al., Journal of Thoracic Oncology, 2017 — DOI — (3 citations)

• Data from A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1 — Sarah A. Weiss, Dijana Djureinovic, Shlomit Jessel, Irina Krykbaeva, et al., 2023 — DOI — (0 citations)

• Supplemental Figure 2A from A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1 — Sarah A. Weiss, Dijana Djureinovic, Shlomit Jessel, Irina Krykbaeva, et al., 2023 — DOI — (0 citations)

• Trial Protocol from A Phase I Study of APX005M and Cabiralizumab with or without Nivolumab in Patients with Melanoma, Kidney Cancer, or Non–Small Cell Lung Cancer Resistant to Anti-PD-1/PD-L1 — Sarah A. Weiss, Dijana Djureinovic, Shlomit Jessel, Irina Krykbaeva, et al., 2023 — DOI — (0 citations)

Top papers by citation count, fetched from OpenAlex. Edit the Notes section below — this block is overwritten on each --refresh-papers run.

Notes

Hand-edited notes, links to interesting findings, talk recordings, etc.