Synthesis: What Computations Do Astrocytes Perform?

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Source: https://github.com/AllenNeuralDynamics/ComputationalReviewAstrocytes/blob/1a55da0634a3bc04e5688792ed12141ce271d28e/content/14_synthesis.md

Citation anchors captured: 97

Citation contexts

^{1Citationpaper:paper-778045e57b0fTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{6Citationpaper:paper-9f16bd0faa11Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{7Citationpaper:paper-bd699ea0aec5Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{8Citationpaper:paper-da0aeffaf2b1Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{9Citationpaper:paper-9a1be146dacdTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{10Citationpaper:paper-4baefab2ada9Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference} Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}0 Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}1 Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}2 Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP₃R2-dependent somatic/branch transients, IP₃R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}3 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}4 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}5 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}6 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}7 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}8 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{2Citationpaper:paper-b422988f09f8Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}9 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}0 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}1 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}2 Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse. The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}3 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}4 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}5 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}6 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}7 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}8 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{3Citationpaper:paper-9c595c660d61Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}9 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}0 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}1 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}2 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}3 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}4 Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal. Section {ref}sec:in-vivo-dynamics consolidated a reframing that Section {ref}sec:calcium-signaling had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}5 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}6 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}7 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}8 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{4Citationpaper:paper-54c454be2778Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}9 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}0 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}1 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}2 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}3 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}4 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}5 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}6 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}7 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}8 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
^{5Citationpaper:paper-883c8368100cTheme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim. Section {ref}sec:calcium-signaling fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...content/14_synthesis.md:line 8Open reference}9 Theme 4: the astrocyte syncytium redistributes rather than just buffers. Section {ref}sec:gap-junctions-networks established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...
... 47 additional anchors in refs_json

References

[petravicz_2008_jneurosci] paper:paper-778045e57b0f “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[agulhon_2010_science] paper:paper-b422988f09f8 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[petravicz_2014_frontbehav] paper:paper-9c595c660d61 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[agarwal_2017_neuron] paper:paper-54c454be2778 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[srinivasan_2015_natneurosci] paper:paper-883c8368100c “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[fiacco_2007_neuron] paper:paper-9f16bd0faa11 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[shigetomi_2013_neuroscience] paper:paper-bd699ea0aec5 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[poskanzer_2016_procnatl] paper:paper-da0aeffaf2b1 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[bojarskaite_2020_natcommun] paper:paper-9a1be146dacd “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[ingiosi_2022_clocksamp] paper:paper-4baefab2ada9 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[henneberger_2010_nature] paper:paper-5525e0e4dcd1 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[henneberger_2020_neuron] paper:paper-f2c64f4579f9 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[durkee_2021_trendsneurosciences] paper:paper-05bd7b9585c9 “**Theme 1: astrocyte calcium is compartmentalised, and the compartment determines the claim.** Section {ref}`sec:calcium-signaling` fixed a three-compartment vocabulary — IP3R2-dependent somatic/branch transients, IP3R2-independent perisynaptic microdomain events, and endfoot signals at the vasculature — and every downstream cluster depended on using it consistently. In Section {ref}`sec:gliotr...”
[ventura_1999_jneurosci] paper:paper-79447c102381 “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[bellesi_2015_bmcbiol] paper:paper-6c1ee79fd5da “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[bergles_1999_currentopinion] paper:paper-ab249997739b “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[wallraff_2006_jneurosci] paper:paper-9ebb7ba6c393 “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[pannasch_2011_procnatl] paper:paper-0f527a7c15ed “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[pannasch_2014_natneurosci] paper:paper-c11b37ea96eb “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[larsen_2014_glia] paper:paper-01f966defe1a “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[kofuji_2021_annurev] paper:paper-15912c20e37a “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[diamond_2001_jneurosci] paper:paper-15da8412e86e “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[scimemi_2014_frontcell] paper:paper-0f68db7ac577 “**Theme 2: astrocytes are a powerful, low-controversy regulator of the chemical environment of the synapse.** The firmest claim the review supports is that astrocytes shape the synaptic micro-environment — glutamate concentration, K+, extracellular volume, and GABA tone — through mechanisms whose biophysics is essentially uncontested, whose genetic perturbations produce concordant phenotypes across laboratories, and...”
[paukert_2014_neuron] paper:paper-23d7b31898ec “**Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal.** Section {ref}`sec:in-vivo-dynamics` consolidated a reframing that Section {ref}`sec:calcium-signaling` had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...”
[ye_2020_natcommun] paper:paper-c96835af4a7d “**Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal.** Section {ref}`sec:in-vivo-dynamics` consolidated a reframing that Section {ref}`sec:calcium-signaling` had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...”
[reimer_2016_natcommun] paper:paper-b2ddc04345ff “**Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal.** Section {ref}`sec:in-vivo-dynamics` consolidated a reframing that Section {ref}`sec:calcium-signaling` had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...”
[reitman_2023_natneurosci] paper:paper-aa304d547310 “**Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal.** Section {ref}`sec:in-vivo-dynamics` consolidated a reframing that Section {ref}`sec:calcium-signaling` had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...”
[stobart_2018_neuron] paper:paper-1b56aab49663 “**Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal.** Section {ref}`sec:in-vivo-dynamics` consolidated a reframing that Section {ref}`sec:calcium-signaling` had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...”
[gray_2021_sciadv] paper:paper-032bfdbbef5c “**Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal.** Section {ref}`sec:in-vivo-dynamics` consolidated a reframing that Section {ref}`sec:calcium-signaling` had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...”
[foley_2017_frontneural] paper:paper-5b51faba247f “**Theme 3: in awake cortex, astrocyte calcium is a slow-timescale state signal.** Section {ref}`sec:in-vivo-dynamics` consolidated a reframing that Section {ref}`sec:calcium-signaling` had already anticipated: in head-fixed awake mice, cortical astrocyte calcium is dominated by locomotion, pupil-indexed arousal, and noradrenergic drive rather than by fine sensory input, with cerebellar Bergmann glia showing the stro...”
[rash_2001_jneurosci] paper:paper-f2e1693bc7b3 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[altevogt_2004_jneurosci] paper:paper-094367a4c6d9 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[houades_2008_jneurosci] paper:paper-ba3b3cda80d2 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[rouach_2008_science] paper:paper-3b2355c03bf7 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[langer_2012_glia] paper:paper-946362473bc7 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[baum_2024_iscience] paper:paper-29515899cf63 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[suzuki_2011_cell] paper:paper-1829615f8d75 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[newman_2011_plosone] paper:paper-16e6ed98049d “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[descalzi_2019_communbiol] paper:paper-40aaf6eec5f7 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[bouryjamot_2016_molpsychiatry] paper:paper-baef06af1040 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[lundgaard_2015_natcommun] paper:paper-c0ab0710be9a “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[chuquet_2010_jneurosci] paper:paper-d02beb4568d2 “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”
[dienel_2013_neurochemistry] paper:paper-76190760a4ad “**Theme 4: the astrocyte syncytium redistributes rather than just buffers.** Section {ref}`sec:gap-junctions-networks` established that astrocytes tile cortex into non-overlapping territorial domains but are wired by Cx43/Cx30 gap junctions into a panglial network that moves K+, water, glucose, and lactate across spatial scales the single cell cannot cover [rash_2001_jneurosci, altevogt_2004_jneurosci, houades_2008_...”

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