Morphological Diversity: Basket Cells, Chandelier Cells, and Beyond
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1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference The developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference The developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference The developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated... -
4CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference The developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated... -
5CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference The developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference0. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference1 Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference2. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference3 Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference4. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference5 Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference6. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference7 Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference8. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference9 Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 3CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference0. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference1 Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons 3CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference2. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference3 The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference4 The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference5 The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference6 The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference7 The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference8 The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and... -
3CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference9 Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons 4CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference0, while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference... -
4CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference1 Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons 4CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference2, while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference... -
4CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference3 Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons 4CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference4, while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference... -
4CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference5 Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons 4CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference6, while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference... -
4CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference7 Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons 4CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference8, while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference... -
4CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference9 Whether basket cell connectivity is primarily organized by cortical layer or by postsynaptic target cell type remains unresolved. Evidence for layer-based organization comes from studies showing that PVBC dendrites and axons arborize preferentially within the same layer, with the PV/CB1 GABAergic input ratio differing between pyramidal tract and contralateral-projecting neurons 5CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference0 (DOI: 10.1523/... -
5CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference1 Whether basket cell connectivity is primarily organized by cortical layer or by postsynaptic target cell type remains unresolved. Evidence for layer-based organization comes from studies showing that PVBC dendrites and axons arborize preferentially within the same layer, with the PV/CB1 GABAergic input ratio differing between pyramidal tract and contralateral-projecting neurons 5CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference2 (DOI: 10.1523/... -
5CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference3 Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata 5CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference4. The... -
5CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference5 Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata 5CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference6. The... -
5CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference7 Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata 5CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference8. The... -
5CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference9 Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference0. The... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference1 Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference2. The... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference3 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference4. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference5 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference6. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference7 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference8. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference9 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference0. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference1 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference2. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference3 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference4. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference5 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference6. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference7 PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference8. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference9 Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed “cartridges” — that can be visualized in light microscopy 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference0. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference1 Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed “cartridges” — that can be visualized in light microscopy 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference2. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference3 Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed “cartridges” — that can be visualized in light microscopy 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference4. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference5 Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed “cartridges” — that can be visualized in light microscopy 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference6. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference7 Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed “cartridges” — that can be visualized in light microscopy 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference8. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of... -
2CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference9 Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference0, yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference1 Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference2, yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference3 Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference4, yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference5 Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference6, yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort... -
1CitationThe developmental cascades that specify PV interneuron identity ({ref}
sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference7 Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number 1CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 2CitationThe developmental cascades that specify PV interneuron identity ({ref}sec-developmental-origins) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...content/04_morphological_diversity.md:line 4Open reference, 6CitationAmong PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...content/04_morphological_diversity.md:line 8Open reference8, yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort... -
... 42 additional anchors in refs_json
References
- [BecerraHernandez2026cortical] “The developmental cascades that specify PV interneuron identity ({ref}`sec-developmental-origins`) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...”
- [Rozov2024dialectics] “The developmental cascades that specify PV interneuron identity ({ref}`sec-developmental-origins`) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...”
- [Bartholome2020composite] “The developmental cascades that specify PV interneuron identity ({ref}`sec-developmental-origins`) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...”
- [Gouwens2020integrated] “The developmental cascades that specify PV interneuron identity ({ref}`sec-developmental-origins`) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...”
- [Yuste2020community] “The developmental cascades that specify PV interneuron identity ({ref}`sec-developmental-origins`) yield neurons that, despite sharing a common molecular signature, diverge dramatically in their axonal architecture and synaptic targeting. This morphological diversity — encompassing large basket, small basket, nest basket, and chandelier cells — determines which compartment of a pyramidal neuron receives PV-mediated...”
- [Milicevic2024physiological] “Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...”
- [Zhang2020hyperactivated] “Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...”
- [NagyPal2023structural] “Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...”
- [Somogyi2025synaptic] “Among PV interneurons, large basket cells (LBCs) represent the most extensively characterized morphological subtype, distinguished by expansive axonal arbors that form dense perisomatic synapses onto the somata and proximal dendrites of pyramidal neurons [BecerraHernandez2026cortical, Rozov2024dialectics, Milicevic2024physiological]. This perisomatic targeting positions LBCs as gatekeepers of pyramidal cell output:...”
- [Liu2024temporal] “The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and...”
- [Morabito2024dendritic] “The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and...”
- [Burton2024fast] “The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and...”
- [Fekete2025synaptic] “The dendritic integration properties of PVBCs are specialized for speed and fidelity. Fast-spiking basket cell dendrites perform both supralinear and sublinear dendritic integration depending on input synchrony, with synchronous inputs more effectively eliciting action potentials while asynchronous inputs generate more spikes for suprathreshold stimuli — nonlinearity mediated by their larger dendritic diameters and...”
- [RoviraEsteban2020semilunar] “Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons [RoviraEsteban2020semilunar], while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference...”
- [Nakano2018parvalbumin] “Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons [RoviraEsteban2020semilunar], while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference...”
- [Grosser2021parvalbumin] “Basket cell connectivity is not indiscriminate but shows input-specific and region-specific organization. In the dentate gyrus, semilunar granule cells provide approximately 50% of perisomatic excitatory innervation onto PV interneurons [RoviraEsteban2020semilunar], while in the striatum, thalamic inputs preferentially target proximal dendrites of PV interneurons whereas cortical inputs show no positional preference...”
- [Jezequel2025cadherins] “Whether basket cell connectivity is primarily organized by cortical layer or by postsynaptic target cell type remains unresolved. Evidence for layer-based organization comes from studies showing that PVBC dendrites and axons arborize preferentially within the same layer, with the PV/CB1 GABAergic input ratio differing between pyramidal tract and contralateral-projecting neurons [NagyPal2023structural] (DOI: 10.1523/...”
- [Mao2024multimodal] “Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata [BecerraHernandez2026cortical, Bartholome2020composite, Mao2024multimodal]. The...”
- [Scala2019layer] “Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata [BecerraHernandez2026cortical, Bartholome2020composite, Mao2024multimodal]. The...”
- [Shi2023laminar] “Beyond the classical large basket cell, PV interneurons encompass several morphological variants with distinct axonal architectures. Small basket cells (SBCs) have more compact axonal arbors forming denser local perisomatic innervation, while nest basket cells (NBCs) produce interleaved, less structured ramifications around target somata [BecerraHernandez2026cortical, Bartholome2020composite, Mao2024multimodal]. The...”
- [Mathieu2026uncovering] “PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules [Rozov2024dialectics, Fekete2025synaptic, NagyPal2023structural, Somogyi2025synaptic]. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin...”
- [Patino2024transcriptomic] “PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules [Rozov2024dialectics, Fekete2025synaptic, NagyPal2023structural, Somogyi2025synaptic]. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin...”
- [Patino2022single] “PVBCs and CCKBCs represent complementary perisomatic inhibitory systems that differ in temporal dynamics, modulation, and connectivity rules [Rozov2024dialectics, Fekete2025synaptic, NagyPal2023structural, Somogyi2025synaptic]. The PV/CB1 GABAergic input ratio is larger on somatic membrane of pyramidal tract neurons compared to contralateral-projecting neurons, suggesting that target-cell-type-specific wiring distin...”
- [Jung2022cortical] “Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed "cartridges" — that can be visualized in light microscopy [Jung2022cortical, BecerraHernandez2026cortical, Qi2024specific]. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of...”
- [Qi2024specific] “Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed "cartridges" — that can be visualized in light microscopy [Jung2022cortical, BecerraHernandez2026cortical, Qi2024specific]. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of...”
- [Inan2013dense] “Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed "cartridges" — that can be visualized in light microscopy [Jung2022cortical, BecerraHernandez2026cortical, Qi2024specific]. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of...”
- [Raudales2024specific] “Chandelier cells (ChCs), also termed axo-axonic cells (AACs), are the only interneuron type that specifically innervates axon initial segments, forming characteristic arrays of boutons — termed "cartridges" — that can be visualized in light microscopy [Jung2022cortical, BecerraHernandez2026cortical, Qi2024specific]. Each chandelier cell contacts 35–50% of pyramidal neurons within its axonal arbor, with an average of...”
- [Wang2012characterization] “Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number [Inan2013dense], yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort...”
- [Butt2017role] “Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number [Inan2013dense], yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort...”
- [Gao2025continuous] “Individual chandelier cells maintain similar innervation patterns across postnatal development from P18 to P90, with relatively small lateral expansions of the axonal arbor and increases in total cartridge number [Inan2013dense], yet cartridge structure varies quantitatively across brain regions: axo-axonic cartridge density and GAT1 innervation per synapse are significantly higher in piriform cortex than in neocort...”
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