Synaptic Properties and Connectivity
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1CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference The intrinsic electrophysiological properties examined in{ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti... -
2CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference The intrinsic electrophysiological properties examined in{ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti... -
3CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference The intrinsic electrophysiological properties examined in{ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti... -
4CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference The intrinsic electrophysiological properties examined in{ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference The intrinsic electrophysiological properties examined in{ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti... -
6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference. This contrasts sharply with the depressing excitatory inputs received by parval...
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7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference. This contrasts sharply with the depressing excitatory inputs received by parval...
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8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 2CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference0. This contrasts sharply with the depressing excitatory inputs received by parval... -
2CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference1 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 2CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference2. This contrasts sharply with the depressing excitatory inputs received by parval... -
2CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference3 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 2CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference4. This contrasts sharply with the depressing excitatory inputs received by parval... -
2CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference5 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 2CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference6. This contrasts sharply with the depressing excitatory inputs received by parval... -
2CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference7 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 2CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference8. This contrasts sharply with the depressing excitatory inputs received by parval... -
2CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference9 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 3CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference0. This contrasts sharply with the depressing excitatory inputs received by parval... -
3CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference1 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 3CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference2. This contrasts sharply with the depressing excitatory inputs received by parval... -
3CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference3 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 3CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference4. This contrasts sharply with the depressing excitatory inputs received by parval... -
3CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference5 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 3CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference6. This contrasts sharply with the depressing excitatory inputs received by parval... -
3CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference7 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 3CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference8. This contrasts sharply with the depressing excitatory inputs received by parval... -
3CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference9 Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing 4CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference0. This contrasts sharply with the depressing excitatory inputs received by parval... -
4CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference1 The molecular mechanisms underlying this facilitation have begun to be elucidated. 4CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference2 identified that GluK2-containing kainate receptors (KARs) and mGluR7 at pyramidal-to-SST synapses are jointly required for short-term facilitation; removal of both receptor types eliminates facilitation and reduces SST-mediated inhibition in somatosensory cortex. This mechanistic specificity suggests that facilitation... -
4CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference3 The molecular mechanisms underlying this facilitation have begun to be elucidated. 4CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference4 identified that GluK2-containing kainate receptors (KARs) and mGluR7 at pyramidal-to-SST synapses are jointly required for short-term facilitation; removal of both receptor types eliminates facilitation and reduces SST-mediated inhibition in somatosensory cortex. This mechanistic specificity suggests that facilitation... -
4CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference5 The molecular mechanisms underlying this facilitation have begun to be elucidated. 4CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference6 identified that GluK2-containing kainate receptors (KARs) and mGluR7 at pyramidal-to-SST synapses are jointly required for short-term facilitation; removal of both receptor types eliminates facilitation and reduces SST-mediated inhibition in somatosensory cortex. This mechanistic specificity suggests that facilitation... -
4CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference7 However, the generality of facilitation as a universal property of all excitatory inputs to all SST subtypes has been challenged by recent subtype-resolved recordings. 4CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference8 found that VIP→SST synapses in both somatosensory and visual cortex show heterogeneous short-term plasticity: some connections exhibit facilitation, others stable responses, and still others depression, with this heterogeneity depending o... -
4CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference9 However, the generality of facilitation as a universal property of all excitatory inputs to all SST subtypes has been challenged by recent subtype-resolved recordings. 5CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference0 found that VIP→SST synapses in both somatosensory and visual cortex show heterogeneous short-term plasticity: some connections exhibit facilitation, others stable responses, and still others depression, with this heterogeneity depending o... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference1 However, the generality of facilitation as a universal property of all excitatory inputs to all SST subtypes has been challenged by recent subtype-resolved recordings. 5CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference2 found that VIP→SST synapses in both somatosensory and visual cortex show heterogeneous short-term plasticity: some connections exhibit facilitation, others stable responses, and still others depression, with this heterogeneity depending o... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference3 Short-term facilitation at pyramidal→SST synapses across studies. Four of five studies report consistent facilitation, while one recent study reveals subtype-dependent heterogeneity. Metric definitions vary across entries; values should be compared qualitatively rather than quantitatively. Sample sizes are not reported for all studies; statistical weighting is not possible. Comparison includes data from different sp... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference4 Short-term facilitation at pyramidal→SST synapses across studies. Four of five studies report consistent facilitation, while one recent study reveals subtype-dependent heterogeneity. Metric definitions vary across entries; values should be compared qualitatively rather than quantitatively. Sample sizes are not reported for all studies; statistical weighting is not possible. Comparison includes data from different sp... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference5 Short-term facilitation at pyramidal→SST synapses across studies. Four of five studies report consistent facilitation, while one recent study reveals subtype-dependent heterogeneity. Metric definitions vary across entries; values should be compared qualitatively rather than quantitatively. Sample sizes are not reported for all studies; statistical weighting is not possible. Comparison includes data from different sp... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference6 Short-term facilitation at pyramidal→SST synapses across studies. Four of five studies report consistent facilitation, while one recent study reveals subtype-dependent heterogeneity. Metric definitions vary across entries; values should be compared qualitatively rather than quantitatively. Sample sizes are not reported for all studies; statistical weighting is not possible. Comparison includes data from different sp... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference7 Short-term facilitation at pyramidal→SST synapses across studies. Four of five studies report consistent facilitation, while one recent study reveals subtype-dependent heterogeneity. Metric definitions vary across entries; values should be compared qualitatively rather than quantitatively. Sample sizes are not reported for all studies; statistical weighting is not possible. Comparison includes data from different sp... -
5CitationThe intrinsic electrophysiological properties examined in {ref}
sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference8 Computational models have incorporated this facilitation as a key circuit feature. 5CitationThe intrinsic electrophysiological properties examined in {ref}sec-intrinsic-electrophysiologydetermine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...content/06_synaptic_connectivity.md:line 3Open reference9 optimized spiking network models and found that facilitating SST synapses were essential for reproducing cortical response properties, while 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference0 analyzed circuit models showing that the facilitating dynamics at pyramidal-to-SST synapses create delayed inhibition that is critical for temporal filtering in cortical c... -
6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference1 Computational models have incorporated this facilitation as a key circuit feature. 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference2 optimized spiking network models and found that facilitating SST synapses were essential for reproducing cortical response properties, while 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference3 analyzed circuit models showing that the facilitating dynamics at pyramidal-to-SST synapses create delayed inhibition that is critical for temporal filtering in cortical c...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference4 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference5. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference6 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference7. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference8 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference9. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference0 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference1. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference2 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference3. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference4 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference5. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference6 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference7. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference8 The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference9. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...
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7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference0 Yet the apparent universality of this motif conceals substantial quantitative heterogeneity. 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference1 reported that approximately substantial of tested SST cells were inhibited by VIP cells in both somatosensory and visual cortex using paired whole-cell recordings (n = 40), while 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference2 reported connection rates as high as 80% in rat neocortex. This nearly twofold range in connection probability across studie...
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7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference3 Yet the apparent universality of this motif conceals substantial quantitative heterogeneity. 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference4 reported that approximately substantial of tested SST cells were inhibited by VIP cells in both somatosensory and visual cortex using paired whole-cell recordings (n = 40), while 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference5 reported connection rates as high as 80% in rat neocortex. This nearly twofold range in connection probability across studie...
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7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference6 Yet the apparent universality of this motif conceals substantial quantitative heterogeneity. 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference7 reported that approximately substantial of tested SST cells were inhibited by VIP cells in both somatosensory and visual cortex using paired whole-cell recordings (n = 40), while 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference8 reported connection rates as high as 80% in rat neocortex. This nearly twofold range in connection probability across studie...
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7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference9 Yet the apparent universality of this motif conceals substantial quantitative heterogeneity. 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference0 reported that approximately substantial of tested SST cells were inhibited by VIP cells in both somatosensory and visual cortex using paired whole-cell recordings (n = 40), while 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference1 reported connection rates as high as 80% in rat neocortex. This nearly twofold range in connection probability across studie...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference2 VIP→SST connection probability across brain areas and studies. Quantitative estimates range from substantial (paired recordings, mouse S1/V1) to ~80% (rat neocortex), while qualitative assessments confirm preferential targeting. Studies span different brain regions; direct quantitative comparison should be interpreted with caution. Metric definitions vary across entries; values should be compared qualitatively rathe...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference3 VIP→SST connection probability across brain areas and studies. Quantitative estimates range from substantial (paired recordings, mouse S1/V1) to ~80% (rat neocortex), while qualitative assessments confirm preferential targeting. Studies span different brain regions; direct quantitative comparison should be interpreted with caution. Metric definitions vary across entries; values should be compared qualitatively rathe...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference4 The synaptic dynamics of VIP→SST connections add further complexity. 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference5 found that VIP→SST short-term plasticity differs between cortical areas and SST subtypes, with some connections showing depression and others facilitation during high-frequency stimulation. 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference6 demonstrated that VIP→Martinotti cell synapses can undergo causal long-term depression (LTD) that is presynaptically expressed, sugg...
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6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference7 The synaptic dynamics of VIP→SST connections add further complexity. 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference8 found that VIP→SST short-term plasticity differs between cortical areas and SST subtypes, with some connections showing depression and others facilitation during high-frequency stimulation. 6CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 7CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 9CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference, 10CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference9 demonstrated that VIP→Martinotti cell synapses can undergo causal long-term depression (LTD) that is presynaptically expressed, sugg...
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8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference0 The synaptic dynamics of VIP→SST connections add further complexity. 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference1 found that VIP→SST short-term plasticity differs between cortical areas and SST subtypes, with some connections showing depression and others facilitation during high-frequency stimulation. 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference2 demonstrated that VIP→Martinotti cell synapses can undergo causal long-term depression (LTD) that is presynaptically expressed, sugg...
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8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference3 The synaptic dynamics of VIP→SST connections add further complexity. 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference4 found that VIP→SST short-term plasticity differs between cortical areas and SST subtypes, with some connections showing depression and others facilitation during high-frequency stimulation. 8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference5 demonstrated that VIP→Martinotti cell synapses can undergo causal long-term depression (LTD) that is presynaptically expressed, sugg...
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8CitationAmong the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...content/06_synaptic_connectivity.md:line 7Open reference6 The outputs of SST interneurons are not monolithic. As detailed in
{ref}sec-morphological-diversity, the Martinotti/non-Martinotti distinction maps onto fundamentally different output targeting strategies, and recent subtype-resolved connectivity mapping has revealed that even within these broad categories, individual SST subtypes show selective input-output relationships [Wu2023, Naka2019, Silberberg2007, Simonne... -
... 77 additional anchors in refs_json
References
- [Baldi2025] “The intrinsic electrophysiological properties examined in {ref}`sec-intrinsic-electrophysiology` determine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...”
- [Singh2023] “The intrinsic electrophysiological properties examined in {ref}`sec-intrinsic-electrophysiology` determine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...”
- [Schuman2021] “The intrinsic electrophysiological properties examined in {ref}`sec-intrinsic-electrophysiology` determine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...”
- [Rachel2025] “The intrinsic electrophysiological properties examined in {ref}`sec-intrinsic-electrophysiology` determine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...”
- [Wu2023] “The intrinsic electrophysiological properties examined in {ref}`sec-intrinsic-electrophysiology` determine how SST interneurons transform synaptic input into output — but what inputs do they receive, and where do they send their inhibition? SST interneurons occupy a distinctive position in cortical circuitry, receiving facilitating excitatory inputs that make them responsive to sustained activity, providing dendriti...”
- [Beierlein2003] “Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...”
- [Silberberg2007] “Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...”
- [Simonnet2017] “Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...”
- [Stachniak2023] “Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...”
- [Gentet2012] “Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...”
- [Keijser2022] “Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...”
- [Bos2025] “Among the most replicated findings in SST interneuron physiology is that excitatory synapses from local pyramidal neurons onto SST cells exhibit short-term facilitation — a progressive increase in postsynaptic response amplitude during repetitive presynaptic firing [Beierlein2003, Silberberg2007, Simonnet2017, Stachniak2023, Gentet2012]. This contrasts sharply with the depressing excitatory inputs received by parval...”
- [Morabito2024] “The molecular mechanisms underlying this facilitation have begun to be elucidated. [Stachniak2023] identified that GluK2-containing kainate receptors (KARs) and mGluR7 at pyramidal-to-SST synapses are jointly required for short-term facilitation; removal of both receptor types eliminates facilitation and reduces SST-mediated inhibition in somatosensory cortex. This mechanistic specificity suggests that facilitation...”
- [Wall2016] “The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience [Wall2016, Marchionni2022, Baldi2025, Jiang2024b]. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...”
- [Marchionni2022] “The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience [Wall2016, Marchionni2022, Baldi2025, Jiang2024b]. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...”
- [Jiang2024b] “The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience [Wall2016, Marchionni2022, Baldi2025, Jiang2024b]. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...”
- [Bogaj2023] “The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience [Wall2016, Marchionni2022, Baldi2025, Jiang2024b]. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...”
- [Song2025a] “The finding that VIP interneurons preferentially inhibit SST interneurons — creating a disinhibitory pathway through which VIP activation releases pyramidal cells from SST-mediated dendritic inhibition — is among the most replicated circuit motifs in cortical neuroscience [Wall2016, Marchionni2022, Baldi2025, Jiang2024b]. it has been established this motif using optogenetic activation of VIP interneurons in mouse vi...”
- [Mao2024] “Yet the apparent universality of this motif conceals substantial quantitative heterogeneity. [Rachel2025] reported that approximately substantial of tested SST cells were inhibited by VIP cells in both somatosensory and visual cortex using paired whole-cell recordings (n = 40), while [Mao2024] reported connection rates as high as 80% in rat neocortex. This nearly twofold range in connection probability across studie...”
- [Marvan2024] “Yet the apparent universality of this motif conceals substantial quantitative heterogeneity. [Rachel2025] reported that approximately substantial of tested SST cells were inhibited by VIP cells in both somatosensory and visual cortex using paired whole-cell recordings (n = 40), while [Mao2024] reported connection rates as high as 80% in rat neocortex. This nearly twofold range in connection probability across studie...”
- [McFarlan2024] “The synaptic dynamics of VIP→SST connections add further complexity. [Rachel2025] found that VIP→SST short-term plasticity differs between cortical areas and SST subtypes, with some connections showing depression and others facilitation during high-frequency stimulation. [McFarlan2024] demonstrated that VIP→Martinotti cell synapses can undergo causal long-term depression (LTD) that is presynaptically expressed, sugg...”
- [Kim2023] “The synaptic dynamics of VIP→SST connections add further complexity. [Rachel2025] found that VIP→SST short-term plasticity differs between cortical areas and SST subtypes, with some connections showing depression and others facilitation during high-frequency stimulation. [McFarlan2024] demonstrated that VIP→Martinotti cell synapses can undergo causal long-term depression (LTD) that is presynaptically expressed, sugg...”
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