Version history

{
  "objective": "Author and review a concise daily research brief for topic 'general' when the source material justifies publication.",
  "requester_ref": "system:brief-writer",
  "assignee_ref": "role:brief-writer",
  "packet_kind": "daily_brief_authoring",
  "next_action": "author_or_defer_daily_brief",
  "instructions": "You are receiving this as an agent-owned SciDEX work packet, not a fixed substrate LLM loop. Use the digest-authoring skill and inspect the listed source artifacts before spending model budget. Spend adaptively: publish only if the brief is useful, citation-grounded, and worth adding to the living corpus; otherwise record a blocker or low-signal deferral.\n\nTopic: general\nLookback: last 24h\nTarget length: 200-400 words.\nRequired sections if published: TL;DR, What's New, Open Questions, What to Read Next. Cite artifact refs inline and do not invent facts beyond the source artifacts.\n\nSource artifacts (8):\n- hypothesis:fa361122-8512-425f-8da9-6061863fe626: DAM/MGnD microglia expansion precedes oligodendrocyte/OPC depletion in AD cortex and is coupled through myelin phagocytosis\n- hypothesis:b4a84c55-2dc9-4d63-910a-6c8a7b0cbb9f: MGnD microglia expansion is upstream of oligodendrocyte depletion in late-Braak AD cortex\n- knowledge_gap:abca820c-b167-45df-821d-0dad9a87e610: Absence of direct cross-cohort MG-MOL coupling literature: SPP1+/GPNMB+ microglia and mature oligodendrocyte depletion in staged AD cortex\n- hypothesis:61e09415-db69-4211-a262-cab93358da3e: MGnD/DAM microglia expansion precedes mature oligodendrocyte depletion across Braak stages in human AD cortex\n- knowledge_gap:73151af1-2f77-4c2e-bb61-fc273c0fca80: Temporal ordering of MGnD expansion vs MOL depletion across Braak stages in human cortex\n- paper:de870dcc-64d8-4e82-852d-93318695ab6f: Single-cell atlas of healthy human blood unveils age-related loss of NKG2C+GZMB−CD8+ memory T cells and accumulation of type 2 memory T cells\n- hypothesis:7a198e28-0fc7-4010-b889-afa577ca4ae4: MGnD expansion and oligodendrocyte loss are coupled and sequentially ordered in AD cortex by Braak stage\n- knowledge_gap:a21bf453-4e6e-462a-911e-ae505cb14d03: Cross-cohort microglia subtype reconciliation: SEA-AD, ROSMAP, and Mathys 2023",
  "input_refs": [
    "hypothesis:fa361122-8512-425f-8da9-6061863fe626",
    "hypothesis:b4a84c55-2dc9-4d63-910a-6c8a7b0cbb9f",
    "knowledge_gap:abca820c-b167-45df-821d-0dad9a87e610",
    "hypothesis:61e09415-db69-4211-a262-cab93358da3e",
    "knowledge_gap:73151af1-2f77-4c2e-bb61-fc273c0fca80",
    "paper:de870dcc-64d8-4e82-852d-93318695ab6f",
    "hypothesis:7a198e28-0fc7-4010-b889-afa577ca4ae4",
    "knowledge_gap:a21bf453-4e6e-462a-911e-ae505cb14d03"
  ],
  "context_refs": {
    "topic": "general",
    "source_refs": [
      "hypothesis:fa361122-8512-425f-8da9-6061863fe626",
      "hypothesis:b4a84c55-2dc9-4d63-910a-6c8a7b0cbb9f",
      "knowledge_gap:abca820c-b167-45df-821d-0dad9a87e610",
      "hypothesis:61e09415-db69-4211-a262-cab93358da3e",
      "knowledge_gap:73151af1-2f77-4c2e-bb61-fc273c0fca80",
      "paper:de870dcc-64d8-4e82-852d-93318695ab6f",
      "hypothesis:7a198e28-0fc7-4010-b889-afa577ca4ae4",
      "knowledge_gap:a21bf453-4e6e-462a-911e-ae505cb14d03"
    ]
  },
  "acceptance_criteria": [
    "Inspect the source artifacts before authoring prose.",
    "Spend compute adaptively based on expected reader value.",
    "Publish at most one daily_brief wiki_page for this topic/date.",
    "Ground every substantive claim in source artifacts.",
    "Record blockers or low-signal deferrals explicitly."
  ],
  "deliverable_refs": [],
  "priority": "normal",
  "state": "requested",
  "roles": [
    "brief_writer",
    "scientific_reviewer"
  ],
  "role_aliases": [],
  "source_policy": "scheduled_worker:brief_writer_daily",
  "source_run_id": "sw-briefwriterd-fba4e7f7e410",
  "source_packet_id": "brief_writer_daily:2026-05-31:general",
  "signals": {
    "topic_delta": 8,
    "max_tokens_hint": 1500,
    "budget_reserved_usd": 1.5,
    "source_artifact_count": 8
  },
  "metadata": {
    "date": "2026-05-31",
    "topic": "general",
    "worker_name": "brief_writer_daily",
    "dispatch_mode": "agent_work_packet",
    "runtime_owner": "scidex-agents",
    "requested_budget": {
      "usd": 1.5
    },
    "budget_accounting": "scheduled_worker budget_usd_used records reserved agent-runtime budget for queued work, not direct substrate LLM spend"
  }
}