Spatially Resolved Oligodendrocyte-Astrocyte Communication Networks Disrupted in Early AD

What spatially resolved cell-cell communication networks between oligodendrocytes and astrocytes are disrupted in early Alzheimer's disease prior to clinical symptoms, and do oligodendrocyte precursor cell states identified by spatial transcriptomics predict subsequent tau propagation from entorhinal cortex?

open neurodegeneration · Alzheimer disease Created Apr 27, 2026

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