DPP6 GWAS Signal: Cell-Type Regulatory Networks for PD Cognitive Decline

What cell-type-specific gene regulatory networks mediate the DPP6 GWAS signal for cognitive decline in Parkinson's disease — do they converge on synaptic plasticity pathways in hippocampal versus prefrontal neurons, and is DPP6 expression altered in prodromal PD before motor symptoms?

failed neurodegeneration · Parkinson disease Created Apr 27, 2026

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