Genetic Aging Landscape Variants and Epigenetic Aging in PD Neuronal Subtypes

Do PD-associated genetic aging landscape variants causally accelerate epigenetic clock rates in specific neuronal subtypes (dopaminergic vs GABAergic vs cholinergic), and can single-nucleus multi-omic profiling of post-mortem PD brain resolve cell-type-specific epigenetic age acceleration?

open neurodegeneration · Parkinson disease Created Apr 27, 2026

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