How can AQP4 be effectively targeted therapeutically to improve neurological outcomes in CNS disorders?

While the abstract identifies AQP4 as a 'potential and promising target' and mentions it could provide 'new therapeutic alternatives,' the specific approaches for therapeutic modulation of AQP4 function are not defined. This represents a critical translational gap for moving from mechanistic understanding to clinical intervention. Gap type: open_question Source paper: Aquaporin-4 in glymphatic system, and its implication for central nervous system disorders. (2023, Neurobiol Dis, PMID:36796590)

archived neurodegeneration Created Apr 7, 2026

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