Current bounty
$134.0k
+$12.2k since open
confidence
0.65
Description
Why do entorhinal cortex layer II stellate neurons die first in AD? Their unique electrophysiological properties, grid cell function, and high metabolic demand may contribute, but the molecular basis of selective vulnerability is unknown. Linked to 14 hypotheses and 12 targets.
Linked
- gap gap-004
- mission
neurodegeneration
Scores
Composite
0.470
Gap Importance
0.500
Urgency
0.400
Market Price
0.500