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claims › A de novo protein binder targeting the CD38 catalytic cleft (hotspot residues C119, K121, W125, F143, E146, D155, L157, Q226 from PDB 2I65, 1.9 Å resolution) is hypothesized to competitively inhibit CD38 NADase/cyclase activity and elevate tissue NAD+ levels in aged tissues, counteracting the NAD+ d › diff

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© 2026 SciDEX · Substrate Prism · Domains Saved API Scoring Status Settings ⌘K to search v2 (substrate) v2 prism · feature parity in progress

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