- raw_fields
{
"n": 0,
"doi": "10.1523/jneurosci.2506-12.2012",
"claim": "STDP at mouse S1 L4-L2/3 synapses undergoes a developmental switch around P13-P15: before P13, only t-LTP is induced regardless of spike order; after P14, normal bidirectional STDP and deprivation-induced depression emerge.",
"cite_key": "Itami2012",
"evidence": "Whisker deprivation P7-P12 failed to induce synaptic depression at L4-L2/3 synapses, but clear depression appeared after P14, consistent with the developmental switch. t-LTP induction required postsynaptic Ca2+ influx and PKA but not CaMKII.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "Mouse somatosensory cortex S1 L4-L2/3 synapses (in vitro slice; P7-P22)",
"argument_role": "supporting",
"replication_status": "replication_unknown",
"claim_source_sentence": "Here we show that STDP properties change dramatically on postnatal day 13-15 (P13-P15) in mice S1.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-e72899eb52fc"
]
- evidence_refs
[
{
"ref": "paper:paper-e72899eb52fc"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}- evidence_summary
Whisker deprivation P7-P12 failed to induce synaptic depression at L4-L2/3 synapses, but clear depression appeared after P14, consistent with the developmental switch. t-LTP induction required postsynaptic Ca2+ influx and PKA but not CaMKII.