Activity-dependent plasticity of E→E connections in mouse cortex: Hebbian, anti…

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Activity-dependent plasticity of E→E connections in mouse cortex: Hebbian, anti-Hebbian, structural plasticity revealed by chronic two-photon and EM

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  • 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 8Citationpaper:paper-dcc9c3699911{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 9Citationpaper:paper-f7c06ba53cae{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference0 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference1 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference2 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference3 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference4 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference5 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference6 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference7 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference8 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 2Citationpaper:paper-673cb5de6c80{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference9 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference0 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference1 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference2 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference3 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference4 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference5 {ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference6 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference7 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference8 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 3Citationpaper:paper-e72899eb52fc{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference9 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference0 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference1 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference2 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference3 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference4 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference5 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference6 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference7 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference8 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 4Citationpaper:paper-4dc12b2ece86{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference9 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference0 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference1 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference2 Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference3 showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...

  • 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference4 The clearest demonstration that experience gates the slice-measured rule is in mouse barrel cortex. 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference5 paired L4 stimulation with post-synaptic spikes in L2/3 pyramidal neurons and reported that, in cortex of undeprived adolescents, the probability of inducing LTP was 33% and the probability of inducing LTD with the same protocol was 49% (see {ref}fig-sec12-stdp-deprivation-barrel). After seven days...

  • 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference6 The clearest demonstration that experience gates the slice-measured rule is in mouse barrel cortex. 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference7 paired L4 stimulation with post-synaptic spikes in L2/3 pyramidal neurons and reported that, in cortex of undeprived adolescents, the probability of inducing LTP was 33% and the probability of inducing LTD with the same protocol was 49% (see {ref}fig-sec12-stdp-deprivation-barrel). After seven days...

  • 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference8 The clearest demonstration that experience gates the slice-measured rule is in mouse barrel cortex. 5Citationpaper:paper-2838da5fb3b7{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference9 paired L4 stimulation with post-synaptic spikes in L2/3 pyramidal neurons and reported that, in cortex of undeprived adolescents, the probability of inducing LTP was 33% and the probability of inducing LTD with the same protocol was 49% (see {ref}fig-sec12-stdp-deprivation-barrel). After seven days...

  • 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference0 The clearest demonstration that experience gates the slice-measured rule is in mouse barrel cortex. 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference1 paired L4 stimulation with post-synaptic spikes in L2/3 pyramidal neurons and reported that, in cortex of undeprived adolescents, the probability of inducing LTP was 33% and the probability of inducing LTD with the same protocol was 49% (see {ref}fig-sec12-stdp-deprivation-barrel). After seven days...

  • 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference2 The clearest demonstration that experience gates the slice-measured rule is in mouse barrel cortex. 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference3 paired L4 stimulation with post-synaptic spikes in L2/3 pyramidal neurons and reported that, in cortex of undeprived adolescents, the probability of inducing LTP was 33% and the probability of inducing LTD with the same protocol was 49% (see {ref}fig-sec12-stdp-deprivation-barrel). After seven days...

  • 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference4 The clearest demonstration that experience gates the slice-measured rule is in mouse barrel cortex. 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference5 paired L4 stimulation with post-synaptic spikes in L2/3 pyramidal neurons and reported that, in cortex of undeprived adolescents, the probability of inducing LTP was 33% and the probability of inducing LTD with the same protocol was 49% (see {ref}fig-sec12-stdp-deprivation-barrel). After seven days...

  • 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference6 The clearest demonstration that experience gates the slice-measured rule is in mouse barrel cortex. 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference7 paired L4 stimulation with post-synaptic spikes in L2/3 pyramidal neurons and reported that, in cortex of undeprived adolescents, the probability of inducing LTP was 33% and the probability of inducing LTD with the same protocol was 49% (see {ref}fig-sec12-stdp-deprivation-barrel). After seven days...

  • 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference8 STDP induction at mouse barrel-cortex L4→L2/3 synapses with and without whisker deprivation. Per-protocol probabilities of LTP and LTD induction at L4→L2/3 pairs reported by 6Citationpaper:paper-7c6cf53ea9e2{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference9. All values are from a single study; the undeprived versus deprived contrast is within-experiment, not cross-laboratory replication.

  • 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference0 The STDP rule in mouse cortex is not single-valued: it differs by layer, pathway, and developmental stage, and at L2/3 horizontal connections appears to involve mechanisms partly distinct from those at the L4→L2/3 vertical input. 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference1 reported that, although t-LTD at vertical L4→L2/3 inputs requires presynaptic NMDA receptors and is expressed presynaptically, t-LTD at L2/3↔L2/3 horizontal inputs requires p...

  • 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference2 The STDP rule in mouse cortex is not single-valued: it differs by layer, pathway, and developmental stage, and at L2/3 horizontal connections appears to involve mechanisms partly distinct from those at the L4→L2/3 vertical input. 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference3 reported that, although t-LTD at vertical L4→L2/3 inputs requires presynaptic NMDA receptors and is expressed presynaptically, t-LTD at L2/3↔L2/3 horizontal inputs requires p...

  • 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference4 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference5 reported that t-LTD at vertical L4→L2/3 inputs depends on presynaptic NMDARs with presynaptic expression, whereas t-LTD at horizontal L2/3↔L2/3 inputs depends on postsynaptic NMDARs with postsynaptic expression. 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference6 agrees with the postsynaptic locus at the horizontal pathway but specifies a GluN2B requirement, leaving the receptor subunit at the vertical pathway and the relation bet...

  • 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference7 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference8 reported that t-LTD at vertical L4→L2/3 inputs depends on presynaptic NMDARs with presynaptic expression, whereas t-LTD at horizontal L2/3↔L2/3 inputs depends on postsynaptic NMDARs with postsynaptic expression. 7Citationpaper:paper-f0807984e9f3{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference9 agrees with the postsynaptic locus at the horizontal pathway but specifies a GluN2B requirement, leaving the receptor subunit at the vertical pathway and the relation bet...

  • 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference0 A second conflict concerns the presynaptic NMDAR mechanism at the vertical pathway itself. 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference1 argues that L5 pyramid-to-pyramid t-LTD in mouse visual cortex relies on non-ionotropic presynaptic NMDAR signalling via JNK2/STX1a — that is, on a signalling action that does not require Ca²⁺ flux through the receptor — whereas the 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference2 account at the vertical L4→L2/3 pathway invokes a canonical iono...

  • 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference3 A second conflict concerns the presynaptic NMDAR mechanism at the vertical pathway itself. 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference4 argues that L5 pyramid-to-pyramid t-LTD in mouse visual cortex relies on non-ionotropic presynaptic NMDAR signalling via JNK2/STX1a — that is, on a signalling action that does not require Ca²⁺ flux through the receptor — whereas the 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference5 account at the vertical L4→L2/3 pathway invokes a canonical iono...

  • 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference6 A second conflict concerns the presynaptic NMDAR mechanism at the vertical pathway itself. 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference7 argues that L5 pyramid-to-pyramid t-LTD in mouse visual cortex relies on non-ionotropic presynaptic NMDAR signalling via JNK2/STX1a — that is, on a signalling action that does not require Ca²⁺ flux through the receptor — whereas the 1Citationpaper:paper-f74ca76e5851{ref}sec-pattern-completion showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}sec-paired-recording are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...content/12_plasticity.md:line 5Open reference8 account at the vertical L4→L2/3 pathway invokes a canonical iono...

  • ... 201 additional anchors in refs_json

References

  1. [Hardingham2011] paper:paper-f74ca76e5851 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  2. [Banerjee2009] paper:paper-673cb5de6c80 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  3. [Itami2012] paper:paper-e72899eb52fc “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  4. [Banerjee2014] paper:paper-4dc12b2ece86 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  5. [Thomazeau2025] paper:paper-2838da5fb3b7 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  6. [Damour2015] paper:paper-7c6cf53ea9e2 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  7. [AndradeTalavera2024] paper:paper-f0807984e9f3 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  8. [Lebida2017] paper:paper-dcc9c3699911 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  9. [Gambino2012] paper:paper-f7c06ba53cae “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  10. [Williams2019] paper:paper-55f18434021b “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  11. [Hedrick2022] paper:paper-c45090fcfe26 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  12. [Majewska2006] paper:paper-904b9c8800c1 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  13. [Holtmaat2008] paper:paper-c73c3d15b3f5 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  14. [Qiao2022] paper:paper-97ea3fb38f38 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  15. [Roth2020] paper:paper-9c3c6ccd1d29 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  16. [Albarran2021] paper:paper-5788e3e6aa69 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  17. [Shao2021] paper:paper-95b8dca171dd “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  18. [Tsimring2025] paper:paper-9361f12c3198 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  19. [LopezOrtega2024] paper:paper-be49e5cccec4 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  20. [Bauer2024] paper:paper-2baf7d052ecd “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  21. [Madar2025] paper:paper-f4dca894ec53 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  22. [Yaeger2025] paper:paper-38eccb12e037 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  23. [Wright2025] paper:paper-317f66a4cd6e “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  24. [Loewenstein2015] paper:paper-32164922d2a1 “{ref}`sec-pattern-completion` showed that recurrent read-outs — pattern completion, replay, sequence reactivation — depend on a structured matrix of E→E weights. This section asks how the weight distributions inventoried in {ref}`sec-paired-recording` are written and updated. The empirical record on mouse cortical E→E plasticity is uneven. Hebbian LTP/LTD and spike-timing-dependent plasticity (STDP) are well-mapped...”
  25. [Field2020] paper:paper-f0f65022899a “Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, [Banerjee2009] showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...”
  26. [Araya2014] paper:paper-838df624220f “Slice paired-recording established that the canonical Hebbian rules — frequency-dependent LTP/LTD and millisecond-precision STDP — operate at multiple mouse cortical E→E layer pairs. At the L4→L2/3 pathway of barrel cortex, [Banerjee2009] showed a double dissociation by NMDAR subunit, with a GluN2A-preferring antagonist blocking t-LTP but leaving t-LTD intact, separating the induction machinery for the two arms of t...”

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