Version history

{
  "scope": "mouse V1 L2/3 excitatory vs GABAergic neurons, brain-wide ΔG-rabies tracing meta-analysis",
  "claim_text": "In mouse V1, the brain-wide origins and proportions of long-range presynaptic inputs to layer 2/3 excitatory and inhibitory neurons are highly similar, indicating that distal cortical inputs are shared across the principal cell classes in superficial V1 rather than projection-class-specific.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41598-021-82353-7",
    "claim": "In mouse V1, the brain-wide origins and proportions of long-range presynaptic inputs to layer 2/3 excitatory and inhibitory neurons are highly similar, indicating that distal cortical inputs are shared across the principal cell classes in superficial V1 rather than projection-class-specific.",
    "cite_key": "Brown2021",
    "evidence": "Re-analysis of brain-wide monosynaptic rabies (ΔG-rabies) input datasets onto excitatory and GABAergic L2/3 V1 starter populations, applying a hierarchical-ontology comparison method (Allen CCF) to quantify input source overlap, and contrasted with L6 ntsr1 inputs.",
    "effect_size": "Long-range input distributions onto L2/3 excitatory vs inhibitory cells largely overlap; both differ from L6 ntsr1 inputs",
    "text_access": "fulltext",
    "study_system": "mouse V1 L2/3 excitatory vs GABAergic neurons, brain-wide ΔG-rabies tracing meta-analysis",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "Consistent with these previous studies it appears inhibitory and excitatory neurons in L2/3 of mouse V1 receive highly overlapping inputs from distal brain regions.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "It is clear from these data that L6 ntsr1-positive cells are readily distinguishable from upper layer cells based on the profile of their long-range input."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "effect_size": "Long-range input distributions onto L2/3 excitatory vs inhibitory cells largely overlap; both differ from L6 ntsr1 inputs",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-6a7351b1c6b5"
  ],
  "source_span": "Consistent with these previous studies it appears inhibitory and excitatory neurons in L2/3 of mouse V1 receive highly overlapping inputs from distal brain regions.",
  "study_system": "mouse V1 L2/3 excitatory vs GABAergic neurons, brain-wide ΔG-rabies tracing meta-analysis",
  "evidence_refs": [
    {
      "ref": "paper:paper-6a7351b1c6b5"
    }
  ],
  "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Re-analysis of brain-wide monosynaptic rabies (ΔG-rabies) input datasets onto excitatory and GABAergic L2/3 V1 starter populations, applying a hierarchical-ontology comparison method (Allen CCF) to quantify input source overlap, and contrasted with L6 ntsr1 inputs.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}