Details

scope
rat striatum; PHA-L anterograde + TH/IHC + autoradiography
claim_text
Distinct dorsal and ventral midbrain dopaminergic populations differentially project to striatal matrix versus patch compartments, and a non-dopaminergic substantia nigra population provides additional input to the matrix.
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_01_evidence_package.json
effect_size
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-01
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
source_span
Thus, distinct dorsal and ventral sets of midbrain dopaminergic neurons project, respectively, to striatal matrix and patches, and there is a non-dopaminergic mesostriatal projection to the matrix.
study_system
rat striatum; PHA-L anterograde + TH/IHC + autoradiography
section_title
Introduction: Swanson's Loop Hypothesis and Its Intellectual Lineage
evidence_summary
PHA-L anterograde tracing combined with TH immunohistochemistry and mu-opiate receptor autoradiography in rats; identified type A/B/C fibers.
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-01
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_01_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.07-12-03915.1987",
  "claim": "Distinct dorsal and ventral midbrain dopaminergic populations differentially project to striatal matrix versus patch compartments, and a non-dopaminergic substantia nigra population provides additional input to the matrix.",
  "cite_key": "Gerfen1987a",
  "evidence": "PHA-L anterograde tracing combined with TH immunohistochemistry and mu-opiate receptor autoradiography in rats; identified type A/B/C fibers.",
  "effect_size": "",
  "text_access": "abstract_only",
  "study_system": "rat striatum; PHA-L anterograde + TH/IHC + autoradiography",
  "source_cluster_id": "cluster_01",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "Thus, distinct dorsal and ventral sets of midbrain dopaminergic neurons project, respectively, to striatal matrix and patches, and there is a non-dopaminergic mesostriatal projection to the matrix.",
  "replication_evidence_dois": [
    "10.1126/science.2799392"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-35a7b4b56bd0"
]
evidence_refs
[
  {
    "ref": "paper:paper-35a7b4b56bd0"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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