A bout of rhythmic whisker stimulation in awake mice produces a roughly 1-hour…

Details

scope: Awake mouse primary somatosensory cortex L2/3 (in vivo two-photon Ca imaging, RWS stimulation)
claim_text: A bout of rhythmic whisker stimulation in awake mice produces a roughly 1-hour increase in whisker-evoked L2/3 neuronal activity in primary somatosensory cortex, consistent with LTP-like potentiation in vivo.
section_id: section_12
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_12_evidence_package.json
effect_size: 1 h sustained increase in whisker-evoked L2/3 activity
review_repo: ComputationalReviewRecurrence
section_ref: wiki_page:computationalreviewrecurrence-12-plasticity
source_kind: review_finding
source_path: evidence/section_12_evidence_package.json
source_span: We found that RWS induced a 1 h increase in whisker-evoked L2/3 neuronal activity in most cells.
study_system: Awake mouse primary somatosensory cortex L2/3 (in vivo two-photon Ca imaging, RWS stimulation)
section_title: 12. Plasticity at E→E synapses in mouse — Hebbian, STDP, behavioural-time-scale plasticity; how plasticity shapes the recurrent matrix during learning
evidence_summary: Time-lapse two-photon Ca imaging in awake mouse S1 showed a 1-hour increase in whisker-evoked activity in L2/3 after rhythmic whisker stimulation, absent for whiskers connected to distant columns.
review_bundle_ref: analysis_bundle:ab-d9c479db9be9
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-d9c479db9be9
source_artifact_ref: wiki_page:computationalreviewrecurrence-12-plasticity
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_12_evidence_package.json
commit_sha: 79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1523/jneurosci.2189-23.2024",
  "claim": "A bout of rhythmic whisker stimulation in awake mice produces a roughly 1-hour increase in whisker-evoked L2/3 neuronal activity in primary somatosensory cortex, consistent with LTP-like potentiation in vivo.",
  "cite_key": "Williams2025b",
  "evidence": "Time-lapse two-photon Ca imaging in awake mouse S1 showed a 1-hour increase in whisker-evoked activity in L2/3 after rhythmic whisker stimulation, absent for whiskers connected to distant columns.",
  "effect_size": "1 h sustained increase in whisker-evoked L2/3 activity",
  "text_access": "abstract_only",
  "study_system": "Awake mouse primary somatosensory cortex L2/3 (in vivo two-photon Ca imaging, RWS stimulation)",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We found that RWS induced a 1 h increase in whisker-evoked L2/3 neuronal activity in most cells.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "We found that RWS induced a 1 h increase in whisker-evoked L2/3 neuronal activity in most cells."
}

source_refs

[
  "paper:paper-538bb92d6a7a"
]

evidence_refs

[
  {
    "ref": "paper:paper-538bb92d6a7a"
  }
]

source_policy

{
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  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
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  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

A bout of rhythmic whisker stimulation in awake mice produces a roughly 1-hour…

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Replication

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