Version history

{
  "scope": "newborn (P0) mouse cortex, DiI tracing + multi-electrode-array recordings across S1 barrel, M1 and S2",
  "claim_text": "In newborn (P0) mouse brain, DiI tracing reveals that neurons in S1-barrel, M1 and S2 already project through the subplate of one another's areas across cortical plate, L5/6 and subplate compartments, and multi-electrode-array recordings confirm functional weak synaptic connections between subplate and L5/6 within and between these S1↔M1↔S2 areas at the earliest postnatal stage.",
  "raw_fields": {
    "n": 0,
    "doi": "10.3389/fnana.2023.1105998",
    "claim": "In newborn (P0) mouse brain, DiI tracing reveals that neurons in S1-barrel, M1 and S2 already project through the subplate of one another's areas across cortical plate, L5/6 and subplate compartments, and multi-electrode-array recordings confirm functional weak synaptic connections between subplate and L5/6 within and between these S1↔M1↔S2 areas at the earliest postnatal stage.",
    "cite_key": "Gellert2023",
    "evidence": "Paraformaldehyde-fixed newborn mouse brain; carbocyanine (DiI) anterograde and retrograde tracing of axonal projections among S1Bf, M1 and S2; multi-electrode-array extracellular recordings in neocortical slices.",
    "effect_size": "Bidirectional axonal projections among S1Bf, M1, S2 at P0; weak but functional CP–SP and L5/6 synaptic connections.",
    "text_access": "abstract_only",
    "study_system": "newborn (P0) mouse cortex, DiI tracing + multi-electrode-array recordings across S1 barrel, M1 and S2",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "Our experiments demonstrate that already at P0 neurons from the cortical plate (CP), layer 5/6 (L5/6), and the SP of both M1 and S2 send projections through the SP of S1Bf. Reciprocally, neurons from CP to SP of S1Bf send projections through the SP of M1 and S2.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Bidirectional axonal projections among S1Bf, M1, S2 at P0; weak but functional CP–SP and L5/6 synaptic connections.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-d776455bfaaf"
  ],
  "source_span": "Our experiments demonstrate that already at P0 neurons from the cortical plate (CP), layer 5/6 (L5/6), and the SP of both M1 and S2 send projections through the SP of S1Bf. Reciprocally, neurons from CP to SP of S1Bf send projections through the SP of M1 and S2.",
  "study_system": "newborn (P0) mouse cortex, DiI tracing + multi-electrode-array recordings across S1 barrel, M1 and S2",
  "evidence_refs": [
    {
      "ref": "paper:paper-d776455bfaaf"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Paraformaldehyde-fixed newborn mouse brain; carbocyanine (DiI) anterograde and retrograde tracing of axonal projections among S1Bf, M1 and S2; multi-electrode-array extracellular recordings in neocortical slices.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}