- claim_text
In newborn (P0) mouse brain, DiI tracing reveals that neurons in S1-barrel, M1 and S2 already project through the subplate of one another's areas across cortical plate, L5/6 and subplate compartments, and multi-electrode-array recordings confirm functional weak synaptic connections between subplate and L5/6 within and between these S1↔M1↔S2 areas at the earliest postnatal stage.
- raw_fields
{
"n": 0,
"doi": "10.3389/fnana.2023.1105998",
"claim": "In newborn (P0) mouse brain, DiI tracing reveals that neurons in S1-barrel, M1 and S2 already project through the subplate of one another's areas across cortical plate, L5/6 and subplate compartments, and multi-electrode-array recordings confirm functional weak synaptic connections between subplate and L5/6 within and between these S1↔M1↔S2 areas at the earliest postnatal stage.",
"cite_key": "Gellert2023",
"evidence": "Paraformaldehyde-fixed newborn mouse brain; carbocyanine (DiI) anterograde and retrograde tracing of axonal projections among S1Bf, M1 and S2; multi-electrode-array extracellular recordings in neocortical slices.",
"effect_size": "Bidirectional axonal projections among S1Bf, M1, S2 at P0; weak but functional CP–SP and L5/6 synaptic connections.",
"text_access": "abstract_only",
"study_system": "newborn (P0) mouse cortex, DiI tracing + multi-electrode-array recordings across S1 barrel, M1 and S2",
"argument_role": "supporting",
"replication_status": "single_study",
"claim_source_sentence": "Our experiments demonstrate that already at P0 neurons from the cortical plate (CP), layer 5/6 (L5/6), and the SP of both M1 and S2 send projections through the SP of S1Bf. Reciprocally, neurons from CP to SP of S1Bf send projections through the SP of M1 and S2.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-d776455bfaaf"
]
- source_span
Our experiments demonstrate that already at P0 neurons from the cortical plate (CP), layer 5/6 (L5/6), and the SP of both M1 and S2 send projections through the SP of S1Bf. Reciprocally, neurons from CP to SP of S1Bf send projections through the SP of M1 and S2.
- evidence_refs
[
{
"ref": "paper:paper-d776455bfaaf"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}