Version history

{
  "scope": "mouse auditory cortex L5 callosal Parv (CC-Parv) and local Parv interneurons",
  "claim_text": "Mouse auditory-cortex L5 callosal parvalbumin-expressing (CC-Parv) GABAergic neurons differ from neighbouring local L5 Parv neurons: CC-Parv have larger dendritic fields with longer/farther-branching dendrites, delayed action-potential onset at threshold currents, lower firing rates and lower instantaneous frequencies, and altered Kv1.1 expression — establishing CC-Parv as a distinct functional subtype within the broader Parv class with intrinsic properties suited to interhemispheric inhibitory gating.",
  "raw_fields": {
    "n": 0,
    "doi": "10.3389/fncel.2018.00053",
    "claim": "Mouse auditory-cortex L5 callosal parvalbumin-expressing (CC-Parv) GABAergic neurons differ from neighbouring local L5 Parv neurons: CC-Parv have larger dendritic fields with longer/farther-branching dendrites, delayed action-potential onset at threshold currents, lower firing rates and lower instantaneous frequencies, and altered Kv1.1 expression — establishing CC-Parv as a distinct functional subtype within the broader Parv class with intrinsic properties suited to interhemispheric inhibitory gating.",
    "cite_key": "Zurita2018",
    "evidence": "Viral retrograde tracing, biocytin morphology reconstruction and whole-cell patch-clamp electrophysiology of L5 CC-Parv vs L5 Parv neurons in mouse auditory cortex slices.",
    "effect_size": "qualitative — CC-Parv has distinct morpho-electrophysiology from local Parv",
    "text_access": "fulltext",
    "study_system": "mouse auditory cortex L5 callosal Parv (CC-Parv) and local Parv interneurons",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "layer 5 CC-Parv neurons had larger dendritic fields characterized by longer dendrites that branched farther from the soma, whereas layer 5 Parv neurons had smaller dendritic fields characterized by shorter dendrites that branched nearer to the soma. The layer 5 CC-Parv neurons are characterized by delayed action potential (AP) responses to threshold currents, lower firing rates, and lower instantaneous frequencies compared to the layer 5 Parv neurons",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.1093/cercor/bhx025"
    ],
    "effect_size_source_sentence": "larger dendritic fields characterized by longer dendrites that branched farther from the soma"
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "qualitative — CC-Parv has distinct morpho-electrophysiology from local Parv",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-65c3717caa0c"
  ],
  "source_span": "layer 5 CC-Parv neurons had larger dendritic fields characterized by longer dendrites that branched farther from the soma, whereas layer 5 Parv neurons had smaller dendritic fields characterized by shorter dendrites that branched nearer to the soma. The layer 5 CC-Parv neurons are characterized by delayed action potential (AP) responses to threshold currents, lower firing rates, and lower instantaneous frequencies c...",
  "study_system": "mouse auditory cortex L5 callosal Parv (CC-Parv) and local Parv interneurons",
  "evidence_refs": [
    {
      "ref": "paper:paper-65c3717caa0c"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Viral retrograde tracing, biocytin morphology reconstruction and whole-cell patch-clamp electrophysiology of L5 CC-Parv vs L5 Parv neurons in mouse auditory cortex slices.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}