Version history

{
  "scope": "mouse barrel cortex L2/3 pyramidal neurons (slice); paired recordings + extracellular stimulation",
  "claim_text": "Paired recordings between L2/3 mouse barrel-cortex pyramidal neurons confirm that strong excitatory connections are exclusively depressing and that EPSP-amplitude or paired-pulse-ratio properties show no clustering on individual postsynaptic neurons.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1371/journal.pcbi.1011046",
    "claim": "Paired recordings between L2/3 mouse barrel-cortex pyramidal neurons confirm that strong excitatory connections are exclusively depressing and that EPSP-amplitude or paired-pulse-ratio properties show no clustering on individual postsynaptic neurons.",
    "cite_key": "Buchholz2023",
    "evidence": "Paired whole-cell recordings and extracellular stimulation between L2/3 pyramidal neurons in mouse barrel cortex; EPSP amplitudes and paired-pulse ratios analysed across converging inputs.",
    "effect_size": "Strong L2/3 EPSPs depressing; no per-cell clustering of synaptic properties",
    "text_access": "abstract_only",
    "study_system": "mouse barrel cortex L2/3 pyramidal neurons (slice); paired recordings + extracellular stimulation",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "While net short-term plasticity was weak, strong synaptic connections were exclusively depressing.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Importantly, we found no evidence for clustering of synaptic properties on individual neurons."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "effect_size": "Strong L2/3 EPSPs depressing; no per-cell clustering of synaptic properties",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-fd3eb0d9b1fd"
  ],
  "source_span": "While net short-term plasticity was weak, strong synaptic connections were exclusively depressing.",
  "study_system": "mouse barrel cortex L2/3 pyramidal neurons (slice); paired recordings + extracellular stimulation",
  "evidence_refs": [
    {
      "ref": "paper:paper-fd3eb0d9b1fd"
    }
  ],
  "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Paired whole-cell recordings and extracellular stimulation between L2/3 pyramidal neurons in mouse barrel cortex; EPSP amplitudes and paired-pulse ratios analysed across converging inputs.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}