Details

scope
mouse barrel cortex L2/3 pyramidal neurons (slice); paired recordings + extracellular stimulation
section_id
section_05
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
effect_size
Strong L2/3 EPSPs depressing; no per-cell clustering of synaptic properties
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-05-horizontal
source_kind
review_finding
source_path
evidence/section_05_evidence_package.json
source_span
While net short-term plasticity was weak, strong synaptic connections were exclusively depressing.
study_system
mouse barrel cortex L2/3 pyramidal neurons (slice); paired recordings + extracellular stimulation
section_title
5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
evidence_summary
Paired whole-cell recordings and extracellular stimulation between L2/3 pyramidal neurons in mouse barrel cortex; EPSP amplitudes and paired-pulse ratios analysed across converging inputs.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single_study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-05-horizontal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Paired recordings between L2/3 mouse barrel-cortex pyramidal neurons confirm that strong excitatory connections are exclusively depressing and that EPSP-amplitude or paired-pulse-ratio properties show no clustering on individual postsynaptic neurons.
raw_fields
{
  "n": 0,
  "doi": "10.1371/journal.pcbi.1011046",
  "claim": "Paired recordings between L2/3 mouse barrel-cortex pyramidal neurons confirm that strong excitatory connections are exclusively depressing and that EPSP-amplitude or paired-pulse-ratio properties show no clustering on individual postsynaptic neurons.",
  "cite_key": "Buchholz2023",
  "evidence": "Paired whole-cell recordings and extracellular stimulation between L2/3 pyramidal neurons in mouse barrel cortex; EPSP amplitudes and paired-pulse ratios analysed across converging inputs.",
  "effect_size": "Strong L2/3 EPSPs depressing; no per-cell clustering of synaptic properties",
  "text_access": "abstract_only",
  "study_system": "mouse barrel cortex L2/3 pyramidal neurons (slice); paired recordings + extracellular stimulation",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "While net short-term plasticity was weak, strong synaptic connections were exclusively depressing.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Importantly, we found no evidence for clustering of synaptic properties on individual neurons."
}
source_refs
[
  "paper:paper-fd3eb0d9b1fd"
]
evidence_refs
[
  {
    "ref": "paper:paper-fd3eb0d9b1fd"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.