Version history

{
  "scope": "adult mouse isocortex and hippocampal formation",
  "claim_text": "Comprehensive single-cell RNA sequencing of ~1.3 million cells across adult mouse isocortex and hippocampal formation produced a transcriptomic taxonomy revealing a full repertoire of glutamatergic and GABAergic types, including a complete set of glutamatergic types in HPF homologous to all major isocortical subclasses.",
  "raw_fields": {
    "n": 1300000,
    "doi": "10.1016/j.cell.2021.04.021",
    "claim": "Comprehensive single-cell RNA sequencing of ~1.3 million cells across adult mouse isocortex and hippocampal formation produced a transcriptomic taxonomy revealing a full repertoire of glutamatergic and GABAergic types, including a complete set of glutamatergic types in HPF homologous to all major isocortical subclasses.",
    "cite_key": "Yao2021a",
    "evidence": "Whole-isocortex+HPF scRNA-seq with cluster-based taxonomy construction in adult mouse.",
    "effect_size": "~1.3 million cells profiled across adult mouse isocortex and HPF",
    "text_access": "abstract_only",
    "study_system": "adult mouse isocortex and hippocampal formation",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "We profiled ~1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic cell-type taxonomy revealing a comprehensive repertoire of glutamatergic and GABAergic neuron types.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/s41586-018-0654-5",
      "10.1038/s41586-021-03950-0",
      "10.1038/s41586-023-06812-z"
    ],
    "effect_size_source_sentence": "We profiled ~1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic cell-type taxonomy revealing a comprehensive repertoire of glutamatergic and GABAergic neuron types."
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "~1.3 million cells profiled across adult mouse isocortex and HPF",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-4dfe44516146"
  ],
  "source_span": "We profiled ~1.3 million cells covering the entire adult mouse isocortex and HPF and derived a transcriptomic cell-type taxonomy revealing a comprehensive repertoire of glutamatergic and GABAergic neuron types.",
  "study_system": "adult mouse isocortex and hippocampal formation",
  "evidence_refs": [
    {
      "ref": "paper:paper-4dfe44516146"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Whole-isocortex+HPF scRNA-seq with cluster-based taxonomy construction in adult mouse.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}