Details
- scope
- mouse cortex L6 CT → TRN, Ntsr1-Cre × ChR2 line, slice
- claim_text
- 10-Hz photoactivation of Ntsr1-Cre L6 corticothalamic axons in mouse triggers GluN2C-NMDAR-dependent long-term potentiation of TRN excitability via recruitment of T-type Ca²⁺ channels.
- section_id
- section_02
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
- effect_size
- 10 Hz photoactivation train
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-02-anatomy-primer
- source_kind
- review_finding
- source_path
- evidence/section_02_evidence_package.json
- source_span
- Upon repetitive photoactivation (10 Hz trains), GluN2C-NMDARs induced a long-term increase in nRt excitability involving a potentiated recruitment of T-type Cachannels.
- study_system
- mouse cortex L6 CT → TRN, Ntsr1-Cre × ChR2 line, slice
- section_title
- 2. Mouse-cortex anatomy primer — areal map, layer structure, projection-class nomenclature (IT / PT / CT), tools available for E→E dissection (paired patch, Cre lines, two-photon-targeted patch, optogenetics, EM reconstruction)
- evidence_summary
- ChR2 photoactivation of Ntsr1-Cre L6 CT axons in mouse TRN slices with whole-cell recording.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-02-anatomy-primer
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1038/s41598-017-12552-8", "claim": "10-Hz photoactivation of Ntsr1-Cre L6 corticothalamic axons in mouse triggers GluN2C-NMDAR-dependent long-term potentiation of TRN excitability via recruitment of T-type Ca²⁺ channels.", "cite_key": "Fernandez2017", "evidence": "ChR2 photoactivation of Ntsr1-Cre L6 CT axons in mouse TRN slices with whole-cell recording.", "effect_size": "10 Hz photoactivation train", "text_access": "abstract_only", "study_system": "mouse cortex L6 CT → TRN, Ntsr1-Cre × ChR2 line, slice", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Upon repetitive photoactivation (10 Hz trains), GluN2C-NMDARs induced a long-term increase in nRt excitability involving a potentiated recruitment of T-type Cachannels.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Upon repetitive photoactivation (10 Hz trains), GluN2C-NMDARs induced a long-term increase in nRt excitability involving a potentiated recruitment of T-type Cachannels." }- source_refs
[ "paper:paper-723cabb1552c" ]
- evidence_refs
[ { "ref": "paper:paper-723cabb1552c" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }