Version history

{
  "scope": "rate model of mouse V1 with PV, SST, VIP",
  "claim_text": "Recurrent E-PV-SST-VIP rate-network models with experimentally constrained connectivity exhibit inhibitory stabilization and replicate cell-type-specific tuning and gain effects observed in mouse V1.",
  "raw_fields": {
    "n": null,
    "id": "cluster_11_finding_35",
    "doi": "10.1152/jn.00732.2015",
    "pmid": "26740531",
    "year": "2016",
    "claim": "Recurrent E-PV-SST-VIP rate-network models with experimentally constrained connectivity exhibit inhibitory stabilization and replicate cell-type-specific tuning and gain effects observed in mouse V1.",
    "pmcid": "PMC4808082",
    "title": "Inhibitory stabilization and visual coding in cortical circuits with multiple interneuron subtypes",
    "authors": "Litwin-Kumar A, Rosenbaum R, Doiron B.",
    "journal": "Journal of neurophysiology",
    "cite_key": "Litwinkumar2016",
    "evidence": "Stability eigen-analysis and tuning-curve fits to data reproduce experimental optogenetic perturbation results.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "rate model of mouse V1 with PV, SST, VIP",
    "_source_cluster": "cluster_11_computational_models",
    "replication_status": "replicated_independent",
    "_source_cluster_index": 34,
    "claim_source_sentence": "We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity constrained by experimental data.",
    "replication_evidence_dois": [
      "10.1073/pnas.2504164122",
      "10.1371/journal.pcbi.1013469",
      "10.1371/journal.pcbi.1012036",
      "10.1093/cercor/bhae378",
      "10.1007/s00422-021-00894-6"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_12",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "source_kind": "review_finding",
  "source_path": "evidence/section_12_evidence_package.json",
  "source_refs": [
    "paper:paper-8f25714ab7fe"
  ],
  "source_span": "We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity constrained by experimental data.",
  "study_system": "rate model of mouse V1 with PV, SST, VIP",
  "evidence_refs": [
    {
      "ref": "paper:paper-8f25714ab7fe"
    }
  ],
  "section_title": "Computational Models of VIP Circuit Function",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Stability eigen-analysis and tuning-curve fits to data reproduce experimental optogenetic perturbation results.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated_independent",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}