Details
- scope
- rate model of mouse V1 with PV, SST, VIP
- claim_text
- Recurrent E-PV-SST-VIP rate-network models with experimentally constrained connectivity exhibit inhibitory stabilization and replicate cell-type-specific tuning and gain effects observed in mouse V1.
- section_id
- section_12
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-12-computational-models
- source_kind
- review_finding
- source_path
- evidence/section_12_evidence_package.json
- source_span
- We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity constrained by experimental data.
- study_system
- rate model of mouse V1 with PV, SST, VIP
- section_title
- Computational Models of VIP Circuit Function
- evidence_summary
- Stability eigen-analysis and tuning-curve fits to data reproduce experimental optogenetic perturbation results.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- replicated_independent
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-12-computational-models
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (4)
- raw_fields
{ "n": null, "id": "cluster_11_finding_35", "doi": "10.1152/jn.00732.2015", "pmid": "26740531", "year": "2016", "claim": "Recurrent E-PV-SST-VIP rate-network models with experimentally constrained connectivity exhibit inhibitory stabilization and replicate cell-type-specific tuning and gain effects observed in mouse V1.", "pmcid": "PMC4808082", "title": "Inhibitory stabilization and visual coding in cortical circuits with multiple interneuron subtypes", "authors": "Litwin-Kumar A, Rosenbaum R, Doiron B.", "journal": "Journal of neurophysiology", "cite_key": "Litwinkumar2016", "evidence": "Stability eigen-analysis and tuning-curve fits to data reproduce experimental optogenetic perturbation results.", "effect_size": null, "text_access": "abstract_only", "study_system": "rate model of mouse V1 with PV, SST, VIP", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 34, "claim_source_sentence": "We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity constrained by experimental data.", "replication_evidence_dois": [ "10.1073/pnas.2504164122", "10.1371/journal.pcbi.1013469", "10.1371/journal.pcbi.1012036", "10.1093/cercor/bhae378", "10.1007/s00422-021-00894-6" ], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-8f25714ab7fe" ]
- evidence_refs
[ { "ref": "paper:paper-8f25714ab7fe" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }