Version history

{
  "scope": "Awake mice; two-photon axonal imaging of vM1 in vS1 L1.",
  "claim_text": "In mouse, axons of vibrissal motor cortex (vM1) projecting to vibrissal somatosensory cortex (vS1) layer 1 carry whisker-position signals that combine with whisker-touch signals in vS1, demonstrating that long-range cortico-cortical M1→S1 feedback to L1 transmits behaviorally relevant contextual information to tuft dendrites of pyramidal neurons.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/nature11321",
    "claim": "In mouse, axons of vibrissal motor cortex (vM1) projecting to vibrissal somatosensory cortex (vS1) layer 1 carry whisker-position signals that combine with whisker-touch signals in vS1, demonstrating that long-range cortico-cortical M1→S1 feedback to L1 transmits behaviorally relevant contextual information to tuft dendrites of pyramidal neurons.",
    "cite_key": "Petreanu2012",
    "evidence": "Two-photon calcium imaging of vM1 axons in L1 of vS1 in mice palpating objects with whiskers; behavioral object-localization task.",
    "effect_size": "vM1→vS1 L1 axons encode whisker position; vS1 receives convergent touch and motor-position signals.",
    "text_access": "abstract_only",
    "study_system": "Awake mice; two-photon axonal imaging of vM1 in vS1 L1.",
    "argument_role": "supporting",
    "replication_status": "replicated",
    "claim_source_sentence": "When mice palpate objects with their whiskers to localize object features, whisker touch excites vS1, while whisker position is signaled by vM1 axons in L1 of vS1.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1016/j.celrep.2018.04.115"
    ],
    "effect_size_source_sentence": "L1 input is thought to provide 'contextual' information, but the signals transmitted by L1 feedback remain uncharacterized."
  },
  "section_id": "section_08",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "effect_size": "vM1→vS1 L1 axons encode whisker position; vS1 receives convergent touch and motor-position signals.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:6e642f7b-6fa7-42a9-b454-ea57dc61a4e2"
  ],
  "source_span": "When mice palpate objects with their whiskers to localize object features, whisker touch excites vS1, while whisker position is signaled by vM1 axons in L1 of vS1.",
  "study_system": "Awake mice; two-photon axonal imaging of vM1 in vS1 L1.",
  "evidence_refs": [
    {
      "ref": "paper:6e642f7b-6fa7-42a9-b454-ea57dc61a4e2"
    }
  ],
  "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon calcium imaging of vM1 axons in L1 of vS1 in mice palpating objects with whiskers; behavioral object-localization task.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}